Opioid use among female breast cancer patients using different adjuvant endocrine therapy regimens

Opioid use among female breast cancer patients using different adjuvant endocrine therapy regimens Breast Cancer Res Treat (2017) 165:455–465 DOI 10.1007/s10549-017-4348-8 EPIDEMIOLOGY Opioid use among female breast cancer patients using different adjuvant endocrine therapy regimens 1 2 3 4 • • • • Xi Tan Tareq Fabian Camacho Virginia T. LeBaron Leslie J. Blackhall Rajesh Balkrishnan Received: 16 May 2017 / Accepted: 16 June 2017 / Published online: 21 June 2017 Springer Science+Business Media, LLC 2017 Abstract respectively). Opioid use probabilities for those who Purpose To explore differences in opioid use across dif- switched from AI to TAM were higher than those for the ferent adjuvant endocrine therapy (AET) regimens, factors TAM-only and AI-only groups. Opioid use was also sig- associated with opioid use, and the impact of opioid use on nificantly associated with AET non-adherence. Opioid overall survival in female breast cancer patients treated users had a significantly higher risk of death (adjusted with AET. hazard ratio [HR] = 1.59, p\ 0.001). Methods This retrospective study analyzed 2006–2012 Conclusions Switching from AI to TAM was associated SEER-Medicare datasets, following patients for at least with a high likelihood of opioid use. Opioid use was sig- two years from the index date, defined as the first date they nificantly associated with AET non-adherence http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Breast Cancer Research and Treatment Springer Journals

Opioid use among female breast cancer patients using different adjuvant endocrine therapy regimens

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Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media, LLC
Subject
Medicine & Public Health; Oncology
ISSN
0167-6806
eISSN
1573-7217
D.O.I.
10.1007/s10549-017-4348-8
Publisher site
See Article on Publisher Site

Abstract

Breast Cancer Res Treat (2017) 165:455–465 DOI 10.1007/s10549-017-4348-8 EPIDEMIOLOGY Opioid use among female breast cancer patients using different adjuvant endocrine therapy regimens 1 2 3 4 • • • • Xi Tan Tareq Fabian Camacho Virginia T. LeBaron Leslie J. Blackhall Rajesh Balkrishnan Received: 16 May 2017 / Accepted: 16 June 2017 / Published online: 21 June 2017 Springer Science+Business Media, LLC 2017 Abstract respectively). Opioid use probabilities for those who Purpose To explore differences in opioid use across dif- switched from AI to TAM were higher than those for the ferent adjuvant endocrine therapy (AET) regimens, factors TAM-only and AI-only groups. Opioid use was also sig- associated with opioid use, and the impact of opioid use on nificantly associated with AET non-adherence. Opioid overall survival in female breast cancer patients treated users had a significantly higher risk of death (adjusted with AET. hazard ratio [HR] = 1.59, p\ 0.001). Methods This retrospective study analyzed 2006–2012 Conclusions Switching from AI to TAM was associated SEER-Medicare datasets, following patients for at least with a high likelihood of opioid use. Opioid use was sig- two years from the index date, defined as the first date they nificantly associated with AET non-adherence

Journal

Breast Cancer Research and TreatmentSpringer Journals

Published: Jun 21, 2017

References

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