Res. Chem. Intermed.
, Vol. 31, No. 9, pp. 857–866 (2005)
Also available online - www.vsppub.com
One-electron redox reactions of troxerutin in aqueous
, S. KAPOOR
, H. S. MAHAL
and T. MUKHERJEE
Radiation Chemistry and Chemical Dynamics Division, Bhabha Atomic Research Centre,
Mumbai 400 085, India
Radiation Biology Division, Bhabha Atomic Research Centre, Mumbai 400 085, India
Received 25 January 2004; accepted 21 January 2005
Abstract—The oxidation of ﬂavonoids is of great interest because of their action as antioxidants
with the ability to scavenge radicals by means of electron-transfer processes. The redox reactions
of the ﬂavonoid derivative troxerutin, (2-[3,4-bis-(2-hydroxyethoxy) phenyl]-3[[6-deoxy-α-
were investigated over a wide range of conditions, using pulse radiolysis and cyclic voltammetry.
The oxidation mechanism proceeds in sequential steps. One-electron redox potentials for troxerutin
were found to be +1.196, +0.846 and −0.634 V vs. NHE.
Keywords: Troxerutin; pulse radiolysis; electron transfer.
The major free radicals produced upon the irradiation of water are H
These free radicals are very reactive  and react with many inorganic and organic
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