One-electron redox reactions of trifluoperazine in aqueous solutions

One-electron redox reactions of trifluoperazine in aqueous solutions Absolute rate constants have been measured for the reactions of the primary and specific one-electron oxidant radicals with the protonated form of trifluoperazine (TFP). The primary radicals, e- aq and OH·, react with TFP at diffusion controlled rates. The transients thus produced have been characterized. Halogenated aliphatic peroxyl radicals oxidize TFP with rate constants between 107 and 108 dm3 mol-1 s-1, depending on the structure of the peroxyl radical. The reactivity of peroxyl radicals has been found to vary with Taft's inductive parameter. Oxidation of TFP at acidic pH has been studied using stopped-flow technique. The reaction between TFP radical cation and ascorbic acid has also been examined using pulse radiolysis technique. The results indicate that TFP radical cation is repaired by ascorbate. One-electron reduction potential of TFP · + /TFP at pH 3.5 has been calculated to be 0.964 V vs. NHE. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

One-electron redox reactions of trifluoperazine in aqueous solutions

Loading next page...
 
/lp/springer_journal/one-electron-redox-reactions-of-trifluoperazine-in-aqueous-solutions-sPMbe6udCM
Publisher
Springer Journals
Copyright
Copyright © 2003 by VSP 2003
Subject
Chemistry; Inorganic Chemistry; Physical Chemistry
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1163/156856703322539681
Publisher site
See Article on Publisher Site

Abstract

Absolute rate constants have been measured for the reactions of the primary and specific one-electron oxidant radicals with the protonated form of trifluoperazine (TFP). The primary radicals, e- aq and OH·, react with TFP at diffusion controlled rates. The transients thus produced have been characterized. Halogenated aliphatic peroxyl radicals oxidize TFP with rate constants between 107 and 108 dm3 mol-1 s-1, depending on the structure of the peroxyl radical. The reactivity of peroxyl radicals has been found to vary with Taft's inductive parameter. Oxidation of TFP at acidic pH has been studied using stopped-flow technique. The reaction between TFP radical cation and ascorbic acid has also been examined using pulse radiolysis technique. The results indicate that TFP radical cation is repaired by ascorbate. One-electron reduction potential of TFP · + /TFP at pH 3.5 has been calculated to be 0.964 V vs. NHE.

Journal

Research on Chemical IntermediatesSpringer Journals

Published: Oct 17, 2004

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off