OCT in Alzheimer’s disease: thinning of the RNFL and superior hemiretina

OCT in Alzheimer’s disease: thinning of the RNFL and superior hemiretina Graefes Arch Clin Exp Ophthalmol (2017) 255:1827–1835 DOI 10.1007/s00417-017-3715-9 NEUROPHTHALMOLOGY OCT in Alzheimer’s disease: thinning of the RNFL and superior hemiretina 1,2,3 1 1 4 João Paulo Cunha & Rita Proença & Arnaldo Dias-Santos & Rita Almeida & 4 5 2,5,6 2 Helena Águas & Marta Alves & Ana Luísa Papoila & Carlota Louro & António Castanheira-Dinis Received: 7 February 2017 /Revised: 30 May 2017 /Accepted: 5 June 2017 /Published online: 22 June 2017 Springer-Verlag GmbH Germany 2017 Abstract culated, and for overall RT values, the nine Early Treatment Background Peripapillary retinal nerve fiber layer (pRNFL) Diabetic Retinopathy Study (ETDRS) areas were used. A and internal macular layer thinning have been demonstrated in multiple regression analysis was applied to assess the effects Alzheimer’s disease (AD) with optical coherence tomography of disease, age, gender, spherical equivalent, visual acuity, (OCT) studies. The purpose of this study is to compare the intraocular pressure, axial length and blood pressure on pRNFL thickness and overall retinal thickness (RT) in AD pRNFL and overall macular RT. patients with non-AD patients, using spectral domain optical Results A total of 202 subjects, including 50 eyes of 50 pa- coherence tomography (SD-OCT) and determine the sectors tients with http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Graefe's Archive for Clinical and Experimental Ophthalmology Springer Journals

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Springer Berlin Heidelberg
Copyright © 2017 by Springer-Verlag GmbH Germany
Medicine & Public Health; Ophthalmology
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