Occurrence of Multiple Sclerosis After Drug Exposure: Insights From Evidence Mapping

Occurrence of Multiple Sclerosis After Drug Exposure: Insights From Evidence Mapping Drug Saf (2017) 40:823–834 DOI 10.1007/s40264-017-0551-0 ORIGINAL RESEARCH ARTICLE Occurrence of Multiple Sclerosis After Drug Exposure: Insights From Evidence Mapping 1 1 2 • • • Ippazio Cosimo Antonazzo Emanuel Raschi Luca Vignatelli 2,3 4,5 2 1 • • • • Elisa Baldin Trond Riise Roberto D’Alessandro Fabrizio De Ponti Elisabetta Poluzzi Published online: 9 June 2017 Springer International Publishing Switzerland 2017 Abstract reviews): 30 case reports and case series, 24 longitudinal Introduction The role of drugs in the occurrence of multiple studies and four randomized controlled trials. Seven longitu- sclerosis (MS) is perceived to be insufficiently investigated. dinal studies had good (at least 7 out of 9) quality scores, Objective The aim of this study was to map and assess the whereas case reports/case series presented several limitations. evidence on MS occurrence after drug exposure, in order to Half of included articles focused on immunomodulatory drugs identify possible signals of causal association. (etanercept, infliximab and adalimumab), especially in case Methods A search strategy was performed in MEDLINE reports/series, suggesting an association with MS occurrence. and Embase as of July 2016; references consistent with the Contraceptives and antibacterials were investigated in some aim of the study were analysed to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Drug Safety Springer Journals

Occurrence of Multiple Sclerosis After Drug Exposure: Insights From Evidence Mapping

Loading next page...
 
/lp/springer_journal/occurrence-of-multiple-sclerosis-after-drug-exposure-insights-from-aHr9FZGu16
Publisher
Springer International Publishing
Copyright
Copyright © 2017 by Springer International Publishing Switzerland
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-5916
eISSN
1179-1942
D.O.I.
10.1007/s40264-017-0551-0
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial