A nonstochastic heritable cell lethality effect was for the first time used in the practice of biotesting in a model of Saccharomyces yeasts for predicting the hazard of low mutagen doses. It was demonstrated that the heritable cell lethality might be induced by multicomponent mutagens of a technogenic nature, for example, sewage waters of gas-transferring plants. The possibility of extrapolation of the results to multicellular organisms is discussed.
Russian Journal of Genetics – Springer Journals
Published: Mar 20, 2007
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