DOI 10.1007/s10600-018-2403-2 Chemistry of Natural Compounds, Vol. 54, No. 3, May, 2018 NEW SEMI-SYNTHETIC DERIVATIVES OF CAPSAICINOIDS AND THEIR ANTIOXIDANT ACTIVITIES 1 1 1 P. Kumboonma, C. Ruangviriyachai, P. Khansawai, 2 1* P. Karitpattawan, and C. Phaosiri Capsaicin (1, CAP) is one of the major pungent molecules found in hot chili peppers (Capsicum spp.). Besides capsaicin, dihydrocapsaicin (2, DHC) shows a similar burning sensation. A variety of capsaicinoid biological activities has been reported, including stimulation of cardiovascular and respiratory systems as well as suppression of growth of cancer cells [1, 2]. In order to better understand antioxidant activity and the role played by different functional groups apart from the phenolic group of capsaicinoids, four capsaicin and dihydrocapsaicin derivatives were designed and newly synthesized in this work. Dried fruits of Capsicum annuum (1 kg) were purchased from the local market in Khon Kaen, Thailand. The dried fruits of C. annuum were extracted with ethyl acetate. Next, the ethyl acetate extract was concentrated and extracted with NaOH solution. The pH of the basic extract was adjusted to acidic with HCl, and it was further extracted with ethyl acetate. The final ethyl acetate extract was concentrated and purified. The 1:1 mixture of
Chemistry of Natural Compounds – Springer Journals
Published: Jun 7, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera