New resorbable bone fixation. Biomaterials in craniomaxillofacial surgery: present and future

New resorbable bone fixation. Biomaterials in craniomaxillofacial surgery: present and future Metallic implants have been extensively used for osteofixation in craniomaxillofacial surgery (CMF). Although they are mainly inert, the disadvantage of not being resorbable remains. Advances in biomaterials technology led to the development of resorbable polymers composed by monomeric units that are naturally present in the body. Among them are polylactide (PLA), polyglycolide (PGA) and their copolymers (PLGA and P(L/DL)LA). After in-depth studies of the structure of these materials, the self-reinforced (SR) technology has merged to solve their mechanical limitations. SR is based on reinforcing elements within the same material, increasing their strength. Ultra-high strength implants were then manufactured by the SR technique. In CMF surgery, SR devices have been used for over 10 years without reported complications. As advantages, SR devices have shown to be biocompatible, reliable, easily handled, and to have favorable degradation properties. At present, copolymeric SR devices (P(L/DL)LA, BioSorb FX, and PLGA, BioSorb PDX) represent an advance in the clinical application of absorbable devices in CMF surgery. The aim of this review is to give an overall understanding of the ultimate advances in biomaterial research for CMF reconstruction, with emphasis in self-reinforced resorbable devices. We also intend to give insight into new devices, such as SR, tacks and their applicability. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Plastic Surgery Springer Journals

New resorbable bone fixation. Biomaterials in craniomaxillofacial surgery: present and future

Loading next page...
 
/lp/springer_journal/new-resorbable-bone-fixation-biomaterials-in-craniomaxillofacial-E2Zm2TzEtw
Publisher
Springer Journals
Copyright
Copyright © 2004 by Springer-Verlag
Subject
Medicine
ISSN
0930-343X
eISSN
1435-0130
D.O.I.
10.1007/s00238-003-0568-8
Publisher site
See Article on Publisher Site

Abstract

Metallic implants have been extensively used for osteofixation in craniomaxillofacial surgery (CMF). Although they are mainly inert, the disadvantage of not being resorbable remains. Advances in biomaterials technology led to the development of resorbable polymers composed by monomeric units that are naturally present in the body. Among them are polylactide (PLA), polyglycolide (PGA) and their copolymers (PLGA and P(L/DL)LA). After in-depth studies of the structure of these materials, the self-reinforced (SR) technology has merged to solve their mechanical limitations. SR is based on reinforcing elements within the same material, increasing their strength. Ultra-high strength implants were then manufactured by the SR technique. In CMF surgery, SR devices have been used for over 10 years without reported complications. As advantages, SR devices have shown to be biocompatible, reliable, easily handled, and to have favorable degradation properties. At present, copolymeric SR devices (P(L/DL)LA, BioSorb FX, and PLGA, BioSorb PDX) represent an advance in the clinical application of absorbable devices in CMF surgery. The aim of this review is to give an overall understanding of the ultimate advances in biomaterial research for CMF reconstruction, with emphasis in self-reinforced resorbable devices. We also intend to give insight into new devices, such as SR, tacks and their applicability.

Journal

European Journal of Plastic SurgerySpringer Journals

Published: Feb 1, 2004

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off