New circulating genomic variant of Crimean-Congo hemorrhagic fever virus in Iran

New circulating genomic variant of Crimean-Congo hemorrhagic fever virus in Iran Crimean-Congo hemorrhagic fever is a viral infection that is caused by Crimean-Congo hemorrhagic fever virus (CCHFV). On May 27, 2012, a woman became ill after accidentally splashing cow’s blood into her eyes. Serological and molecular investigations were carried out on the serum of the patient. The test results for serological testing were negative, but RT-PCR was strongly positive for CCHFV. A phylogenetic study on the CCHFV genome sequence showed 50 % similarity to a 520-bp region of Russian strains. By combining historical phylogenetic data and current data, it can be surmised that there are potentially more than five circulating CCHFV genomic variants in Iran. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

New circulating genomic variant of Crimean-Congo hemorrhagic fever virus in Iran

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Publisher
Springer Vienna
Copyright
Copyright © 2013 by Springer-Verlag Wien
Subject
Biomedicine; Virology; Medical Microbiology; Infectious Diseases
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s00705-012-1588-0
Publisher site
See Article on Publisher Site

Abstract

Crimean-Congo hemorrhagic fever is a viral infection that is caused by Crimean-Congo hemorrhagic fever virus (CCHFV). On May 27, 2012, a woman became ill after accidentally splashing cow’s blood into her eyes. Serological and molecular investigations were carried out on the serum of the patient. The test results for serological testing were negative, but RT-PCR was strongly positive for CCHFV. A phylogenetic study on the CCHFV genome sequence showed 50 % similarity to a 520-bp region of Russian strains. By combining historical phylogenetic data and current data, it can be surmised that there are potentially more than five circulating CCHFV genomic variants in Iran.

Journal

Archives of VirologySpringer Journals

Published: May 1, 2013

References

  • Surveillance and laboratory detection system of Crimean-Congo haemorrhagic fever in Iran
    Chinikar, S; Goya, M; Shirzadi, M; Ghiasi, S; Mirahmadi, R; Haeri, A

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