Nerve enlargement in an unusual case of inflammatory neuropathy and new gene mutation—morphology is the key

Nerve enlargement in an unusual case of inflammatory neuropathy and new gene... Neurol Sci (2017) 38:1525–1527 DOI 10.1007/s10072-017-2960-3 LETTER TO THE EDITOR Nerve enlargement in an unusual case of inflammatory neuropathy and new gene mutation—morphology is the key 1 1 1 1 Alexander Grimm & Natalie Winter & Stefan Wolking & Debora Vittore & 2 3 Saskia Biskup & Hubertus Axer Received: 27 January 2017 /Accepted: 8 April 2017 /Published online: 19 April 2017 Springer-Verlag Italia 2017 Background Case report Differentiation between hereditary and inflammatory neurop- In 2016, a 53-year-old male presented with a 12-year-history athies sometimes may be challenging as both share some char- of slowly progressive, distally predominant sensory and motor acteristic features. Both, Charcot-Marie-Tooth (CMT1) and neuropathy with reduced/absent deep tendon reflexes. In chronic inflammatory demyelinating polyradiculoneuritis 2014, based on externally acquired NCS with significantly (CIDP) often show distal sensory disturbances and chronic reduced conduction velocities and slightly elevated CSF pro- symptom progression. Reduction of conduction velocity tein, steroids were administered with slight amelioration of (CV) in the nerve conduction studies (NCS) is the main hall- sensory deficits. Due to side effects, this therapy was mark. However, in CIDP focal electrophysiological signs discontinued after several weeks. In the following months, (e.g., conduction blocks), stepwise deterioration and proximal the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neurological Sciences Springer Journals

Nerve enlargement in an unusual case of inflammatory neuropathy and new gene mutation—morphology is the key

Loading next page...
 
/lp/springer_journal/nerve-enlargement-in-an-unusual-case-of-inflammatory-neuropathy-and-Ae0XeSE55e
Publisher
Springer Milan
Copyright
Copyright © 2017 by Springer-Verlag Italia
Subject
Medicine & Public Health; Neurology; Neuroradiology; Neurosurgery; Psychiatry
ISSN
1590-1874
eISSN
1590-3478
D.O.I.
10.1007/s10072-017-2960-3
Publisher site
See Article on Publisher Site

Abstract

Neurol Sci (2017) 38:1525–1527 DOI 10.1007/s10072-017-2960-3 LETTER TO THE EDITOR Nerve enlargement in an unusual case of inflammatory neuropathy and new gene mutation—morphology is the key 1 1 1 1 Alexander Grimm & Natalie Winter & Stefan Wolking & Debora Vittore & 2 3 Saskia Biskup & Hubertus Axer Received: 27 January 2017 /Accepted: 8 April 2017 /Published online: 19 April 2017 Springer-Verlag Italia 2017 Background Case report Differentiation between hereditary and inflammatory neurop- In 2016, a 53-year-old male presented with a 12-year-history athies sometimes may be challenging as both share some char- of slowly progressive, distally predominant sensory and motor acteristic features. Both, Charcot-Marie-Tooth (CMT1) and neuropathy with reduced/absent deep tendon reflexes. In chronic inflammatory demyelinating polyradiculoneuritis 2014, based on externally acquired NCS with significantly (CIDP) often show distal sensory disturbances and chronic reduced conduction velocities and slightly elevated CSF pro- symptom progression. Reduction of conduction velocity tein, steroids were administered with slight amelioration of (CV) in the nerve conduction studies (NCS) is the main hall- sensory deficits. Due to side effects, this therapy was mark. However, in CIDP focal electrophysiological signs discontinued after several weeks. In the following months, (e.g., conduction blocks), stepwise deterioration and proximal the

Journal

Neurological SciencesSpringer Journals

Published: Apr 19, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off