Polyphosphoric acid functionalized silica-coated magnetic nanoparticles with core–shell structure (NiFe2O4@SiO2–PPA) has been used as a magnetically recyclable green catalyst for the one-pot three-component synthesis of 2-thioxoquinazolinones by the reaction of isatoic anhydride, primary amines and thiourea under neat conditions. The catalyst is readily recovered by simple magnetic decantation and can be recycled five times with no significant loss of catalytic activity.
Research on Chemical Intermediates – Springer Journals
Published: Nov 14, 2014
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