Nanofiber-based scaffolds for tissue engineering

Nanofiber-based scaffolds for tissue engineering For successful tissue engineering, it is essential to have as many biomimetic scaffolds as possible. With increasing interest in nanotechnology, development of nanofibers ( n- fibers) by using the technique of electrospinning is having a new momentum. Among important potential applications of n- fiber-based scaffolds for tissue engineering represent an important advancing front. Nanoscaffolds ( n- scaffolds) mimic natural extracellular matrix (ECM) and its nanoscale fibrous structure. With electrospinning, it is possible to develop submicron fibers from biodegradable polymers and these can also be used for developing multifunctional drug-releasing and bioactive scaffolds. Developed n- scaffolds are tested for their cytocompatibility using various cell models. In addition, they were seeded with cells for engineering tissue constructs. There is a large area ahead for further applications and development of these scaffolds. For instance, multifunctional scaffolds that can be used as controlled delivery system do have a potential and have yet to be investigated for improved engineering of various tissues. So far, there are only very few in vivo studies on n- scaffolds, but in the future many are expected to emerge. With the convergence of the fields of nanotechnology, drug release, and tissue engineering, new solutions could be found for the current limitations of tissue engineering. In this paper, nanoscaffolds developed by using electrospinning, used polymers so far, cytocompatibility and applications in tissue engineering are reviewed. European Journal of Plastic Surgery Springer Journals

Nanofiber-based scaffolds for tissue engineering

Loading next page...
Copyright © 2012 by Springer-Verlag
Medicine & Public Health; Plastic Surgery
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial