G Het or Het or Fe O @TiO /Cu O 3 4 2 2 X HN Alkyl Alkyl 100 C/ DMSO KOH X= I, Cl, Br 27 examples Keywords Nano-chemistry Nano-magnetic Green chemistry Heterogeneous catalyst N-Arylation Introduction Transition metal-catalyzed cross-coupling reactions are one of the most efﬁcient and powerful tools in organic synthesis for the connection of two fragments through C– C or C–N bond formation. The development of an efﬁcient methodology for C–N Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2556-1) contains supplementary material, which is available to authorized users. & Firouzeh Nemati email@example.com Department of Chemistry, Semnan University, Semnan, Iran 123 7612 F. Nemati, A. Elhampour bond formation is one of the most important reactions since the resultant N-arylated heterocyclic products play an important role in a wide range of pharmaceuticals and biologically active compounds and natural products . Among the many reported C–N coupling reactions such as Ullmann coupling, Chan–Lam coupling  and Buchwald–Hartwig amination , the Ullmann-type coupling reactions are particularly attractive because they often allow the usage of low-cost starting materials and readily available copper complexes. The Ullmann-type coupling reactions can be mediated by palladium, nickel or copper
Research on Chemical Intermediates – Springer Journals
Published: May 6, 2016
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