Adv Ther (2017) 34:2674–2679 DOI 10.1007/s12325-017-0637-1 ORIGINAL RESEARCH Muscle Relaxants as a Risk Factor for Vis-a`-tergo During Penetrating Keratoplasty: A Prospective Interventional Study . . . Miltiadis Fiorentzis Emanuela Morinello Anja Viestenz . . Hanna Zuche Berthold Seitz Arne Viestenz Received: September 25, 2017 / Published online: November 3, 2017 Springer Healthcare Ltd. 2017 nondepolarizing muscle relaxants. VAT was ABSTRACT assessed 15 min after surgery had begun. Results: When mivacurium was used, IOP Introduction: This study aimed to investigate decreased by 2.2 mmHg [standard deviation the inﬂuence of three muscle relaxants on (SD) ±2.2 mmHg; p\0.001]. Atracurium intraocular pressure (IOP), ocular pulse ampli- decreased the IOP by an average of 5.8 mmHg tude (OPA), and vis-a`-tergo (VAT) in patients (SD ±1.8 mmHg; p\0.001) and rocuronium undergoing penetrating keratoplasty (PKP) caused an IOP reduction of 7.2 mmHg under general anesthesia. (SD ±2 mmHg; p\0.001). The relative IOP Methods: Ninety-ﬁve patients undergoing PKP decrease was 12% with mivacurium, 29% with were included in this prospective single-center atracurium, and 37% with rocuronium interventional study. IOP and OPA were mea- (p\0.001). OPA decreased by 0.6 mmHg with sured with a dynamic contour tonometer before mivacurium (SD ±0.6 mmHg; 26%; p\0.001), and 5 min
Advances in Therapy – Springer Journals
Published: Nov 3, 2017
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