Multiple symmetric lipomatosis as a genetic disorder: a review

Multiple symmetric lipomatosis as a genetic disorder: a review Multiple symmetric lipomatosis (MSL) is a rare disorder characterized by the presence of multiple, symmetric nonencapsulated fat masses in the face, neck, and other areas. The typical presentation of MSL consists of massive lipomatous deposits around the neck which has given rise to the classic description of a buffalo hump or horse collar. The etiology is unknown although autosomal dominant or mitochondrial inheritance has been postulated based on several affected families and tissue studies. We reviewed the current literature and present a 43-year-old male with a circumferential neck mass composed of multiple nonencapsulated lipomas. His family history is unique with eight family members over three generations. European Journal of Plastic Surgery Springer Journals

Multiple symmetric lipomatosis as a genetic disorder: a review

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Copyright © 2012 by Springer-Verlag
Medicine & Public Health; Plastic Surgery
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