Multiple epimutations in imprinted genes in the human genome and congenital disorders

Multiple epimutations in imprinted genes in the human genome and congenital disorders The current knowledge on multiple epimutations in imprinted genes and their impact on the disturbance of human prenatal development and the emergence of hereditary diseases are reviewed and analyzed. Genetic mechanisms regulating the epigenetic state of imprinted loci in the human genome are discussed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

Multiple epimutations in imprinted genes in the human genome and congenital disorders

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Publisher
Pleiades Publishing
Copyright
Copyright © 2014 by Pleiades Publishing, Inc.
Subject
Biomedicine; Human Genetics; Animal Genetics and Genomics; Microbial Genetics and Genomics
ISSN
1022-7954
eISSN
1608-3369
D.O.I.
10.1134/S1022795414030053
Publisher site
See Article on Publisher Site

Abstract

The current knowledge on multiple epimutations in imprinted genes and their impact on the disturbance of human prenatal development and the emergence of hereditary diseases are reviewed and analyzed. Genetic mechanisms regulating the epigenetic state of imprinted loci in the human genome are discussed.

Journal

Russian Journal of GeneticsSpringer Journals

Published: Apr 6, 2014

References

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