Journal of Neurology (2018) 265:1466–1468 https://doi.org/10.1007/s00415-018-8900-1 LE T TER TO THE EDITORS Multifocal motor neuropathy following treatment with adalimumab for ulcerative colitis 1 1 1 1 1 Laura Fionda · Fiammetta Vanoli · Antonella Di Pasquale · Luca Leonardi · Stefania Morino · Giovanni Antonini Received: 10 March 2018 / Revised: 3 May 2018 / Accepted: 5 May 2018 / Published online: 16 May 2018 © Springer-Verlag GmbH Germany, part of Springer Nature 2018 Dear Sirs, nerve, with a distal amplitude of 3.1 mV and a proximal one of 0.8 mV, and a motor conduction velocity of 32.9 m/s Anti-tumor necrosis factor-alpha (anti-TNF-α) monoclonal (Table 1). Sensory and motor NCS was normal in right and antibodies are used in patients with inflammatory bowel left median, ulnar and peroneal nerves. An ultrasound (US) disease . Demyelinating neuropathies are increasingly study showed an increased cross-sectional area (CSA) of reported among patients treated with these agents . Multi- the left radial nerve at the third distal segment in the arm focal motor neuropathy (MMN) is an asymmetric motor neu- (Fig. 1). A systematic US evaluation of the other upper and ropathy with multifocal motor conduction blocks, and anti- lower limb nerves was normal. MRI of brain and cervical GM1 antibodies found in 50% of cases .
Journal of Neurology – Springer Journals
Published: May 16, 2018
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