Multicomponent reaction in deep eutectic solvent for synthesis of substituted 1-aminoalkyl-2-naphthols

Multicomponent reaction in deep eutectic solvent for synthesis of substituted... One-pot multicomponent synthesis of Betti bases (aminoalkyl naphthols) from aldehydes, β-naphthol, and secondary amines in deep eutectic solvent (DES) based on urea and choline chloride has been developed. A broad range of aminoalkyl naphthols can be obtained smoothly in good to excellent yield in biodegradable choline-chloride-based deep eutectic solvent, being compatible with functional groups and operationally straightforward. In addition, DES could be readily recycled at least four times without obvious loss of activity. Research on Chemical Intermediates Springer Journals

Multicomponent reaction in deep eutectic solvent for synthesis of substituted 1-aminoalkyl-2-naphthols

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Springer Netherlands
Copyright © 2016 by Springer Science+Business Media Dordrecht
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
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