Multicentric Chordoma

Multicentric Chordoma Clin Neuroradiol (2018) 28:283–288 DOI 10.1007/s00062-017-0610-z CORRESPONDENCE An Uncommon and Incompletely Understood Presentation 1 2 1 Jason R. Jones · Anita Huttner · Ajay Malhotra Received: 14 May 2017 / Accepted: 12 July 2017 / Published online: 1 August 2017 © Springer-Verlag GmbH Germany 2017 Introduction Case Report Chordoma is a rare neoplasm of the neuraxis, long be- A 75-year-old male with a past medical history of hyperten- lieved to arise from notochord remnants. Its distribution has sion, obstructive sleep apnea and hyperlipidemia presented principally thought to favor the sacrococcygeal region, fol- in October 2011 with speech and tongue dysmotility, occip- lowed by the skull base and then elsewhere discretely along ital pain, and 15 pounds of weight loss. A large clival mass the spine. Although recent data may challenge this pattern, was discovered by magnetic resonance imaging (MRI) and even more infrequently chordomas are seen arising simul- a subsequent computed tomography (CT) guided biopsy re- taneously at multiple points along the neuraxis [1]. Very vealed malignant cells that were consistent with chordoma few cases of multicentric chordoma have been reported. (Figs. 1 and 2). The lesion showed lobulated architecture A more diffuse pattern complicates treatment strategies for and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Klinische Neuroradiologie Springer Journals

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Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer-Verlag GmbH Germany
Subject
Medicine & Public Health; Neuroradiology; Neurosurgery; Neurology
ISSN
0939-7116
eISSN
1869-1447
D.O.I.
10.1007/s00062-017-0610-z
Publisher site
See Article on Publisher Site

Abstract

Clin Neuroradiol (2018) 28:283–288 DOI 10.1007/s00062-017-0610-z CORRESPONDENCE An Uncommon and Incompletely Understood Presentation 1 2 1 Jason R. Jones · Anita Huttner · Ajay Malhotra Received: 14 May 2017 / Accepted: 12 July 2017 / Published online: 1 August 2017 © Springer-Verlag GmbH Germany 2017 Introduction Case Report Chordoma is a rare neoplasm of the neuraxis, long be- A 75-year-old male with a past medical history of hyperten- lieved to arise from notochord remnants. Its distribution has sion, obstructive sleep apnea and hyperlipidemia presented principally thought to favor the sacrococcygeal region, fol- in October 2011 with speech and tongue dysmotility, occip- lowed by the skull base and then elsewhere discretely along ital pain, and 15 pounds of weight loss. A large clival mass the spine. Although recent data may challenge this pattern, was discovered by magnetic resonance imaging (MRI) and even more infrequently chordomas are seen arising simul- a subsequent computed tomography (CT) guided biopsy re- taneously at multiple points along the neuraxis [1]. Very vealed malignant cells that were consistent with chordoma few cases of multicentric chordoma have been reported. (Figs. 1 and 2). The lesion showed lobulated architecture A more diffuse pattern complicates treatment strategies for and

Journal

Klinische NeuroradiologieSpringer Journals

Published: Aug 1, 2017

References

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