Mouse models of deep vein thrombosis

Mouse models of deep vein thrombosis The pathogenesis of venous thromboembolism (VTE) is still not completely understood. Experimental animals in which human deep vein thrombosis can be modeled are useful tools to investigate the pathogenesis of VTE. Besides the availability of transgenic and genetically modified mice, the use of high frequency ultrasound and intravital microscopy plays an important role in identifying thrombotic processes in mouse models. In this article, an overview about the application of various new technologies and existing mouse models is provided, and the impact of venous side branches on deep vein thrombosis in the mouse model is discussed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Gefässchirurgie Springer Journals

Mouse models of deep vein thrombosis

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Publisher
Springer Medizin
Copyright
Copyright © 2016 by The Author(s)
Subject
Medicine & Public Health; Vascular Surgery
ISSN
0948-7034
eISSN
1434-3932
D.O.I.
10.1007/s00772-016-0227-6
Publisher site
See Article on Publisher Site

Abstract

The pathogenesis of venous thromboembolism (VTE) is still not completely understood. Experimental animals in which human deep vein thrombosis can be modeled are useful tools to investigate the pathogenesis of VTE. Besides the availability of transgenic and genetically modified mice, the use of high frequency ultrasound and intravital microscopy plays an important role in identifying thrombotic processes in mouse models. In this article, an overview about the application of various new technologies and existing mouse models is provided, and the impact of venous side branches on deep vein thrombosis in the mouse model is discussed.

Journal

GefässchirurgieSpringer Journals

Published: Dec 12, 2016

References

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