Mammalian Genome 10, 926–929 (1999). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1999 Mouse H-Y encoding Smcy gene and its X Chromosomal homolog Smcx 1 2 1 1,3 2 Alexander I. Agulnik, Guy Longepied, Maria T. Ty, Colin E. Bishop, Michael Mitchell Department of Obstetrics and Gynecology, 6550 Fannin St., Baylor College of Medicine, Houston, Texas 77030, USA INSERM Unite 406, Marseille, France Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA Received: 3 March 1999 / Accepted: 13 May 1999 SMCY is present on the Y in mouse, human, and most mammals. During cDNA isolation we found several splice variants of the Importantly, it is present on the marsupial Y showing that SMCX/ Smcy and Smcx transcripts. Several splice variants of the SMCY SMCY diverged at least 120 Myr years ago (Agulnik et al. 1994a). gene were also recovered from human testis and lymphocyte Unlike many other Y-Chromosomal genes, SMCY is present in a polyA RNA (data not shown). Different transcripts apparently single copy in mouse and man. Both Y and X Chr homologs are utilizing different splice sites have been also reported for the hu- widely transcribed in all male tissues,
Mammalian Genome – Springer Journals
Published: Sep 1, 1999
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