Mammalian Genome 7, $295-$304 (1997). 9 Springer-Verlag New York Inc. 1997 Kenneth R. Johnson,* Muriel T. Davisson** The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609-1500, USA Received: 18 October 1996 As of October 1996, there were 444 loci mapped to Chr 18 in the Four of the genes that are new to this year's report are as- mouse (Table 1); 110 identified as genes or gene-related sequences sociated with phenotypic traits. A targeted null mutation of the and 334 identified as anonymous DNA sequences. Since last Pou4f3 gene (POU domain, class 4, transcription factor 3), year's report, 67 new loci were added; 21 identified as genes and formerly designated Brn-3.1, resulted in complete deafness 47 identified as DNA segments. In addition to these 444 loci, 19 in Pou4f3 -/- mice which was attributed to failure of hair cells to appear in the inner ear (33502). The Eae3 gene (susceptibility chromosomal aberrations involving Chr 18 have been reported and also are included in Table 1. to experimental allergic encephalomyelitis 3) confers resistance The composite genetic map of Chr 18 has been anchored to the to EAE, an autoimmune disease of the central nervous system, centromere by reference to
Mammalian Genome – Springer Journals
Published: Apr 22, 2014
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