Most Breast Cancer Patients with T1-2 Tumors and One to Three Positive Lymph Nodes Do Not Need Postmastectomy Radiotherapy

Most Breast Cancer Patients with T1-2 Tumors and One to Three Positive Lymph Nodes Do Not Need... Ann Surg Oncol (2018) 25:1912–1920 https://doi.org/10.1245/s10434-018-6422-9 OR IG INA L A R TIC L E – BREA S T O NC OLOG Y Most Breast Cancer Patients with T1-2 Tumors and One to Three Positive Lymph Nodes Do Not Need Postmastectomy Radiotherapy 1 1 2 1 Shirin Muhsen, MD , Tracy-Ann Moo, MD , Sujata Patil, PhD , Michelle Stempel, MPH , Simon Powell, MD, 3 1 1 PhD , Monica Morrow, MD , and Mahmoud El-Tamer, MD 1 2 Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY ABSTRACT tumors (p = 0.0013), higher histologic grade (p = 0.029), Background/Objective. Guidelines concur that postmas- more positive LNs (p \ 0.0001), lymphovascular invasion tectomy radiation therapy (PMRT) in T1-2 tumors with one (LVI) (p \ 0.0001), extracapsular nodal extension to three positive (?) lymph nodes (LNs) decreases (p \ 0.0001), and macroscopic LN metastases locoregional recurrence (LRR) but advise limiting PMRT (p \ 0.0001). There was no difference in LRR, RFS, or OS to patients at highest risk to balance http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Surgical Oncology Springer Journals

Most Breast Cancer Patients with T1-2 Tumors and One to Three Positive Lymph Nodes Do Not Need Postmastectomy Radiotherapy

Loading next page...
 
/lp/springer_journal/most-breast-cancer-patients-with-t1-2-tumors-and-one-to-three-positive-XGb2yvMIZ0
Publisher
Springer Journals
Copyright
Copyright © 2018 by Society of Surgical Oncology
Subject
Medicine & Public Health; Surgical Oncology; Oncology; Surgery
ISSN
1068-9265
eISSN
1534-4681
D.O.I.
10.1245/s10434-018-6422-9
Publisher site
See Article on Publisher Site

Abstract

Ann Surg Oncol (2018) 25:1912–1920 https://doi.org/10.1245/s10434-018-6422-9 OR IG INA L A R TIC L E – BREA S T O NC OLOG Y Most Breast Cancer Patients with T1-2 Tumors and One to Three Positive Lymph Nodes Do Not Need Postmastectomy Radiotherapy 1 1 2 1 Shirin Muhsen, MD , Tracy-Ann Moo, MD , Sujata Patil, PhD , Michelle Stempel, MPH , Simon Powell, MD, 3 1 1 PhD , Monica Morrow, MD , and Mahmoud El-Tamer, MD 1 2 Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY ABSTRACT tumors (p = 0.0013), higher histologic grade (p = 0.029), Background/Objective. Guidelines concur that postmas- more positive LNs (p \ 0.0001), lymphovascular invasion tectomy radiation therapy (PMRT) in T1-2 tumors with one (LVI) (p \ 0.0001), extracapsular nodal extension to three positive (?) lymph nodes (LNs) decreases (p \ 0.0001), and macroscopic LN metastases locoregional recurrence (LRR) but advise limiting PMRT (p \ 0.0001). There was no difference in LRR, RFS, or OS to patients at highest risk to balance

Journal

Annals of Surgical OncologySpringer Journals

Published: Mar 21, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off