Molecular structure and developmental expression of two zebrafish Ankylosis Progressive Homolog (ankh) genes, ankha and ankhb

Molecular structure and developmental expression of two zebrafish Ankylosis Progressive Homolog... We isolated two zebrafish ankylosis progressive homolog (ankh) genes, ankha and ankhb, from embryonic zebrafish. Amino acid sequences deduced from zebrafish ankh genes are aligned with orthologue proteins from other species, the results showed that they share high percentage of identities (74–82%). Whole-mount in situ hybridization experiments showed that ankha and ankhb are maternal inherited genes which can be detected at 1-cell stage embryos and express in the entire animal pole from 6 hours post-fertilization (hpf) to 12 hpf. At the later stages (from 24 hpf to 3 dpf), expression of ankha was restricted in head region. In contrast, transcripts of ankhb were observed in head, gut, and pharyngeal arches. In conclusion, the present studies not only help us to comparatively analyze ankh genes across species, but also provide useful information about expressions during early embryogenesis that will help in further investigations of functional studies of Ankh in the future. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Developmental Biology Springer Journals

Molecular structure and developmental expression of two zebrafish Ankylosis Progressive Homolog (ankh) genes, ankha and ankhb

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Publisher
Springer US
Copyright
Copyright © 2013 by Pleiades Publishing, Inc.
Subject
Life Sciences; Developmental Biology; Animal Anatomy / Morphology / Histology
ISSN
1062-3604
eISSN
1608-3326
D.O.I.
10.1134/S1062360413060106
Publisher site
See Article on Publisher Site

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