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- Publisher
- Springer Journals
- Copyright
- Copyright © 2007 by Springer-Verlag
- Subject
- Biomedicine; Virology; Medical Microbiology; Infectious Diseases
- ISSN
- 0304-8608
- eISSN
- 1432-8798
- DOI
- 10.1007/s00705-006-0934-5
- pmid
- 17308978
- Publisher site
- See Article on Publisher Site
Abstract
A phylogenetic analysis of VP1 and VP4 nucleotide sequences of 52 recent CVA16 strains demonstrated two distinct CVA16 genogroups, A and B, with the prototype strain being the only member of genogroup A. CVA16 G-10, the prototype strain, showed a nucleotide difference of 27.7–30.2% and 19.9–25.2% in VP1 and VP4, respectively, in relation to other CVA16 strains, which formed two separate lineages in genogroup B with nucleotide variation of less than 13.4% and less than 16.3% in VP1 and VP4, respectively. Lineage 1 strains circulating before 2000 were later displaced by lineage 2 strains.
Journal
Archives of Virology – Springer Journals
Published: Jun 1, 2007