The discovery of cell-free DNA in the blastocoele fluid is promising for the development of new noninvasive methods for the preimplantation genetic diagnosis of chromosomal diseases. However, there are no data confirming the concordance between the molecular karyotype of cell-free DNA from blastocoele fluid and the blastocyst cells per se. This paper reports on such concordance according to the results of molecular cytogenetic analysis by comparative genomic hybridization.
Russian Journal of Genetics – Springer Journals
Published: Nov 13, 2015
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