Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome

Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome The recently described novel gyroviruses may infect chickens and/or humans; however, their pathogenic potential is unknown. In our metagenomic investigation, we detected many of the novel gyroviruses in the fecal viromes of ferrets with lymph node and organ enlargement. The complete genomic sequences of selected gyrovirus strains showed 90.7-99.4 % similarity to homologous reference gyrovirus strains. This study did not demonstrate an association between gyrovirus shedding from ferrets and the observed background disease; however, it provides evidence for genetic diversity among gyroviruses and raises the possibility that pet ferrets may transmit gyroviruses to heterologous hosts, e.g., humans. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome

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Publisher
Springer Vienna
Copyright
Copyright © 2014 by Springer-Verlag Wien
Subject
Biomedicine; Virology; Medical Microbiology; Infectious Diseases
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s00705-014-2203-3
Publisher site
See Article on Publisher Site

References

  • Discovery of a genome of a distant relative of chicken anemia virus reveals a new member of the genus Gyrovirus
    Rijsewijk, FA; Santos, HF; Teixeira, TF; Cibulski, SP; Varela, AP; Dezen, D; Franco, AC; Roehe, PM

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