Access the full text.
Sign up today, get DeepDyve free for 14 days.
T. Ch’ng, L. Enquist (2005)
Efficient Axonal Localization of Alphaherpesvirus Structural Proteins in Cultured Sympathetic Neurons Requires Viral Glycoprotein EJournal of Virology, 79
S. Chowdhury, M. Onderci, Partha Bhattacharjee, A. Al-Mubarak, Mark Weiss, You Zhou (2002)
Bovine Herpesvirus 5 (BHV-5) Us9 Is Essential for BHV-5 NeuropathogenesisJournal of Virology, 76
Akihisa Kato, Mayuko Yamamoto, Takashi Ohno, H. Kodaira, Y. Nishiyama, Y. Kawaguchi (2005)
Identification of Proteins Phosphorylated Directly by the Us3 Protein Kinase Encoded by Herpes Simplex Virus 1Journal of Virology, 79
M. Lyman, B. Feierbach, D. Curanović, M. Bisher, L. Enquist (2007)
Pseudorabies Virus Us9 Directs Axonal Sorting of Viral CapsidsJournal of Virology, 81
R. Diefenbach, A. Davis, M. Miranda-Saksena, M. Fernandez, Barbara Kelly, Cheryl Jones, J. Lavail, Jing Xue, Joey Lai, A. Cunningham (2015)
The Basic Domain of Herpes Simplex Virus 1 pUS9 Recruits Kinesin-1 To Facilitate Egress from NeuronsJournal of Virology, 90
G. Daniel, P. Sollars, G. Pickard, Gregory Smith (2015)
Pseudorabies Virus Fast Axonal Transport Occurs by a pUS9-Independent MechanismJournal of Virology, 89
J. Tyborowska, Krystyna Bieńkowska-Szewczyk, Michał Rychłowski, J. Oirschot, F. Rijsewijk (2000)
The extracellular part of glycoprotein E of bovine herpesvirus 1 is sufficient for complex formation with glycoprotein I but not for cell-to-cell spreadArchives of Virology, 145
J. Lavail, A. Tauscher, A. Sucher, O. Harrabi, R. Brandimarti (2007)
Viral regulation of the long distance axonal transport of herpes simplex virus nucleocapsidNeuroscience, 146
J Virol
Fushan Wang, W. Tang, Helen McGraw, J. Bennett, L. Enquist, H. Friedman (2005)
Herpes Simplex Virus Type 1 Glycoprotein E Is Required for Axonal Localization of Capsid, Tegument, and Membrane GlycoproteinsJournal of Virology, 79
D. McGeoch, A. Dolan, S. Donald, F. Rixon (1985)
Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1.Journal of molecular biology, 181 1
Y. Nishikawa, X. Xuan, H. Otsuka (1998)
Identification and characterization of the glycoprotein E and I genes of canine herpesvirus.Virus research, 56 1
D. Johnson, V. Feenstra (1987)
Identification of a novel herpes simplex virus type 1-induced glycoprotein which complexes with gE and binds immunoglobulinJournal of Virology, 61
J. O'connor, J. Alwine, C. Lutz (1997)
Identification of a novel, non-snRNP protein complex containing U1A protein.RNA, 3 12
A. Brideau, J. Card, L. Enquist (2000)
Role of Pseudorabies Virus Us9, a Type II Membrane Protein, in Infection of Tissue Culture Cells and the Rat Nervous SystemJournal of Virology, 74
Sita Awasthi, J. Alwine (2003)
Association of polyadenylation cleavage factor I with U1 snRNP.RNA, 9 11
L. Chamberlain (2004)
Detergents as tools for the purification and classification of lipid raftsFEBS Letters, 559
J. Mijnes, B. Lutters, A. Vlot, E. Anken, Marian Horzinek, P. Rottier, R. Groot (1997)
Structure-function analysis of the gE-gI complex of feline herpesvirus: mapping of gI domains required for gE-gI interaction, intracellular transport, and cell-to-cell spreadJournal of Virology, 71
A. Brideau, M. Eldridge, L. Enquist (2000)
Directional Transneuronal Infection by Pseudorabies Virus Is Dependent on an Acidic Internalization Motif in the Us9 Cytoplasmic TailJournal of Virology, 74
J. Card, M. Whealy, A. Robbins, L. Enquist (1992)
Pseudorabies virus envelope glycoprotein gI influences both neurotropism and virulence during infection of the rat visual systemJournal of Virology, 66
R. Kratchmarov, T. Kramer, T. Greco, Matthew Taylor, T. Ch’ng, I. Cristea, L. Enquist (2013)
Glycoproteins gE and gI Are Required for Efficient KIF1A-Dependent Anterograde Axonal Transport of Alphaherpesvirus Particles in NeuronsJournal of Virology, 87
E. Brittle, A. Reynolds, L. Enquist (2004)
Two Modes of Pseudorabies Virus Neuroinvasion and Lethality in MiceJournal of Virology, 78
Gary, Dubin, Saswata Basu, Diana Mallory, Mitali Basu, Ruth Tal-Singer, H. Friedman (1994)
Characterization of domains of herpes simplex virus type 1 glycoprotein E involved in Fc binding activity for immunoglobulin G aggregatesJournal of Virology, 68
M. Whealy, J. Card, A. Robbins, J. Dubin, H. Rziha, L. Enquist (1993)
Specific pseudorabies virus infection of the rat visual system requires both gI and gp63 glycoproteinsJournal of Virology, 67
S. Chowdhury, B. Lee, A. Ozkul, M. Weiss (2000)
Bovine Herpesvirus 5 Glycoprotein E Is Important for Neuroinvasiveness and Neurovirulence in the Olfactory Pathway of the RabbitJournal of Virology, 74
K. Tsujimura, T. Yamanaka, T. Kondo, H. Fukushi, T. Matsumura (2006)
Pathogenicity and immunogenicity of equine herpesvirus type 1 mutants defective in either gI or gE gene in murine and hamster models.The Journal of veterinary medical science, 68 10
Benjamin Weeks, Periasamy Sundaresan, Thandavarayan Nagashunmugam, Eugene Kang, Harvey Friedman (1997)
The herpes simplex virus-1 glycoprotein E (gE) mediates IgG binding and cell-to-cell spread through distinct gE domains.Biochemical and biophysical research communications, 235 1
M. Lyman, C. Kemp, Matthew Taylor, L. Enquist (2009)
Comparison of the Pseudorabies Virus Us9 Protein with Homologs from Other Veterinary and Human AlphaherpesvirusesJournal of Virology, 83
H. Friedman, E. Macarak, R. Macgregor, J. Wolfe, N. Kefalides (1981)
Virus infection of endothelial cells.The Journal of infectious diseases, 143 2
Aleksandra Snyder, K. Polčicová, David Johnson (2008)
Herpes Simplex Virus gE/gI and US9 Proteins Promote Transport of both Capsids and Virion Glycoproteins in Neuronal AxonsJournal of Virology, 82
T. Kramer, T. Greco, Matthew Taylor, A. Ambrosini, I. Cristea, L. Enquist (2012)
Kinesin-3 mediates axonal sorting and directional transport of alphaherpesvirus particles in neurons.Cell host & microbe, 12 6
Syed Rizvi, M. Raghavan (2001)
An N-Terminal Domain of Herpes Simplex Virus Type I gE Is Capable of Forming Stable Complexes with gIJournal of Virology, 75
K. Polčicová, K. Goldsmith, B. Rainish, T. Wisner, David Johnson (2005)
The Extracellular Domain of Herpes Simplex Virus gE Is Indispensable for Efficient Cell-to-Cell Spread: Evidence for gE/gI ReceptorsJournal of Virology, 79
K. Dingwell, C. Brunetti, R. Hendricks, Q. Tang, Mary Tang, A. Rainbow, David Johnson (1994)
Herpes simplex virus glycoproteins E and I facilitate cell-to-cell spread in vivo and across junctions of cultured cellsJournal of Virology, 68
Jun Han, P. Chadha, Jason Starkey, J. Wills (2012)
Function of glycoprotein E of herpes simplex virus requires coordinated assembly of three tegument proteins on its cytoplasmic tailProceedings of the National Academy of Sciences, 109
Claudia Martín, Catherine Liu, M. Kielian (2009)
Dealing with low pH: entry and exit of alphaviruses and flaviviruses.Trends in microbiology, 17 11
L. Enquist, M. Tomishima, S. Gross, Gregory Smith (2002)
Directional spread of an α-herpesvirus in the nervous systemVeterinary Microbiology, 86
A. Farnsworth, David Johnson (2006)
Herpes Simplex Virus gE/gI Must Accumulate in the trans-Golgi Network at Early Times and Then Redistribute to Cell Junctions To Promote Cell-Cell SpreadJournal of Virology, 80
M. Lyman, D. Curanović, L. Enquist (2008)
Targeting of Pseudorabies Virus Structural Proteins to Axons Requires Association of the Viral Us9 Protein with Lipid RaftsPLoS Pathogens, 4
P. Balan, N. Davis-Poynter, S. Bell, H. Atkinson, H. Browne, T. Minson (1994)
An analysis of the in vitro and in vivo phenotypes of mutants of herpes simplex virus type 1 lacking glycoproteins gG, gE, gI or the putative gJ.The Journal of general virology, 75 ( Pt 6)
Helen McGraw, Sita Awasthi, Jason Wojcechowskyj, H. Friedman (2009)
Anterograde Spread of Herpes Simplex Virus Type 1 Requires Glycoprotein E and Glycoprotein I but Not Us9Journal of Virology, 83
Xiaoqiu Huang, W. Miller (1991)
A time-efficient, linear-space local similarity algorithmAdvances in Applied Mathematics, 12
S. Harrison (2008)
The pH sensor for flavivirus membrane fusionThe Journal of Cell Biology, 183
A. Al-Mubarak, S. Chowdhury (2011)
In the absence of glycoprotein I (gI), gE determines bovine herpesvirus type 5 neuroinvasiveness and neurovirulenceJournal of NeuroVirology, 10
Matthew Taylor, T. Kramer, M. Lyman, R. Kratchmarov, L. Enquist (2012)
Visualization of an Alphaherpesvirus Membrane Protein That Is Essential for Anterograde Axonal Spread of Infection in NeuronsmBio, 3
Thomas Arnold, D. Linke (2007)
Phase separation in the isolation and purification of membrane proteins.BioTechniques, 43 4
A. Brideau, T. Rio, E. Wolffe, L. Enquist (1999)
Intracellular Trafficking and Localization of the Pseudorabies Virus Us9 Type II Envelope Protein to Host and Viral MembranesJournal of Virology, 73
Jeffrey Greenfield, Julia Tsai, G. Gouras, Bing Hai, G. Thinakaran, Frédéric Checler, S. Sisodia, Paul Greengard, Huaxi Xu (1999)
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides.Proceedings of the National Academy of Sciences of the United States of America, 96 2
M. Tomishima, L. Enquist (2002)
In Vivo Egress of an Alphaherpesvirus from AxonsJournal of Virology, 76
N. Butchi, Clinton Jones, Sandra Perez, A. Doster, S. Chowdhury (2011)
Envelope protein Us9 is required for the anterograde transport of bovine herpesvirus type 1 from trigeminal ganglia to nose and eye upon reactivationJournal of NeuroVirology, 13
H. Dailey, P. Strittmatter (1978)
Structural and functional properties of the membrane binding segment of cytochrome b5.The Journal of biological chemistry, 253 22
R. Brandimarti, B. Roizman (1997)
Us9, a stable lysine-less herpes simplex virus 1 protein, is ubiquitinated before packaging into virions and associates with proteasomes.Proceedings of the National Academy of Sciences of the United States of America, 94 25
L. Zsak, Federico Zuckermann, Nancy Sugg, Tamar Ben, '. Porat (1992)
Glycoprotein gI of pseudorabies virus promotes cell fusion and virus spread via direct cell-to-cell transmissionJournal of Virology, 66
T. Nagashunmugam, J. Lubinski, Liyang Wang, L. Goldstein, B. Weeks, P. Sundaresan, Eugene Kang, G. Dubin, H. Friedman (1998)
In Vivo Immune Evasion Mediated by the Herpes Simplex Virus Type 1 Immunoglobulin G Fc ReceptorJournal of Virology, 72
A. Brideau, B. Banfield, L. Enquist (1998)
The Us9 Gene Product of Pseudorabies Virus, an Alphaherpesvirus, Is a Phosphorylated, Tail-Anchored Type II Membrane ProteinJournal of Virology, 72
D. Lichtenberg, H. Ahyayauch, A. Alonso, F. Goñi (2013)
Detergent solubilization of lipid bilayers: a balance of driving forces.Trends in biochemical sciences, 38 2
T. Kramer, L. Enquist (2013)
Directional Spread of Alphaherpesviruses in the Nervous SystemViruses, 5
J. Whitbeck, A. Knapp, L. Enquist, W. Lawrence, L. Bello (1996)
Synthesis, processing, and oligomerization of bovine herpesvirus 1 gE and gI membrane proteinsJournal of Virology, 70
Xiaoqin Lin, J. Lubinski, H. Friedman (2004)
Immunization Strategies To Block the Herpes Simplex Virus Type 1 Immunoglobulin G Fc ReceptorJournal of Virology, 78
K. Polčicová, P. Biswas, K. Banerjee, T. Wisner, B. Rouse, David Johnson (2005)
Herpes keratitis in the absence of anterograde transport of virus from sensory ganglia to the cornea.Proceedings of the National Academy of Sciences of the United States of America, 102 32
Samik Basu, G. Dubin, Thandavarayan Nagashunmugam, M. Basu, L. Goldstein, Liyang Wang, Benjamin Weeks, Harvey Friedman (1997)
Mapping regions of herpes simplex virus type 1 glycoprotein I required for formation of the viral Fc receptor for monomeric IgG.Journal of immunology, 158 1
Herpes simplex virus type 1 (HSV-1) glycoprotein E (gE), glycoprotein I (gI), and Us9 promote efficient anterograde axonal transport of virus from the neuron cytoplasm to the axon terminus. HSV-1 and PRV gE and gI form a heterodimer that is required for anterograde transport, but an association that includes Us9 has not been demonstrated. NS-gE380 is an HSV-1 mutant that has five amino acids inserted after gE residue 380, rendering it defective in anterograde axonal transport. We demonstrated that gE, gI and Us9 form a trimolecular complex in Vero cells infected with NS-gE380 virus in which gE binds to both Us9 and gI. We detected the complex using immunoprecipitation with anti-gE or anti-gI monoclonal antibodies in the presence of ionic detergents. Under these conditions, Us9 did not associate with gE in cells infected with wild-type HSV-1; however, using a nonionic detergent, TritonX-100, an association between Us9 and gE was detected in immunoprecipitates of both wild-type and NS-gE380-infected cells. The results suggest that the interaction between Us9 and gE is weak and disrupted by ionic detergents in wild-type infected cells. We postulate that the tight interaction between Us9 and gE leads to the anterograde spread defect in the NS-gE380 virus.
Archives of Virology – Springer Journals
Published: Aug 27, 2016
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.