Mod(mdg4)-58.0, the product of mod(mdg4) locus, directly interacts with kermit protein of Drosophila melanogaster

Mod(mdg4)-58.0, the product of mod(mdg4) locus, directly interacts with kermit protein of... The experiments in a yeast two-hybrid system, on co-immunoprecipitation of proteins from the D. melanogaster embryonic cell lysates, and on cell immunostaining have shown for the first time that the product of mod(mdg4) locus, Mod (mdg4)-58.0 (isoform C), directly interacts with Kermit protein (dGIPC). Kermit protein plays an important role in locomotor activity, polarization of the cells within the plane of the epithelium at the early stages of development, transfer of intercellular signals, and determining the longevity of Drosophila. These data expand the understanding of the role of Mod(mdg4)-58.0 protein in the eukaryotic cell activity. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

Mod(mdg4)-58.0, the product of mod(mdg4) locus, directly interacts with kermit protein of Drosophila melanogaster

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Publisher
Pleiades Publishing
Copyright
Copyright © 2017 by Pleiades Publishing, Inc.
Subject
Biomedicine; Human Genetics; Animal Genetics and Genomics; Microbial Genetics and Genomics
ISSN
1022-7954
eISSN
1608-3369
D.O.I.
10.1134/S102279541611003X
Publisher site
See Article on Publisher Site

Abstract

The experiments in a yeast two-hybrid system, on co-immunoprecipitation of proteins from the D. melanogaster embryonic cell lysates, and on cell immunostaining have shown for the first time that the product of mod(mdg4) locus, Mod (mdg4)-58.0 (isoform C), directly interacts with Kermit protein (dGIPC). Kermit protein plays an important role in locomotor activity, polarization of the cells within the plane of the epithelium at the early stages of development, transfer of intercellular signals, and determining the longevity of Drosophila. These data expand the understanding of the role of Mod(mdg4)-58.0 protein in the eukaryotic cell activity.

Journal

Russian Journal of GeneticsSpringer Journals

Published: Feb 7, 2017

References

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