Minoxidil

Minoxidil Reactions 1704, p251 - 2 Jun 2018 Sinus node dysfunction accompanied by syncope: case report A 9-year-old girl developed sinus node dysfunction accompanied by syncope during treatment with minoxidil for alopecia [dosage and duration of treatment to reaction onset not stated]. The girl had been applying topical minoxidil for alopecia for two years. She presented for cardiac assessment before starting systemic minoxidil. She reported syncope once upon giving blood. She underwent cardiac monitoring for 24 hours using Holter monitor and asystolic attacks and sinus arrest were noted lasting for 4–6 seconds, accompanied by one episode of syncope in the morning hours. The girl’s treatment with minoxidil was discontinued. She was hospitalized for monitoring and scheduled for permanent pacemaker implantation. Transesophageal electrophysiological study was performed. After discontinuing minoxidil, the sinus arrest and sinus node dysfunction resolved, with normal sinus node function. Later, she was closely monitored for cardiac function. Implantation of the permanent pacemaker was not performed due to morbidity in paediatrics, and she was discharged home asymptomatically. Author comment: "The sinus node dysfunction experienced in this case was categorized as likely related to minoxidil (score 5), as assessed by the Naranjo adverse drug reaction probability assessment tool." Koca S, et al. Topical minoxidil treatment and sinus node dysfunciton in a child patient. Eastern Journal of Medicine 23: 121-123, No. 2, Apr-Jun 2018. Available from: URL: http://doi.org/10.5505/ejm.2018.47955 - Turkey 803322941 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Minoxidil

Reactions Weekly , Volume 1704 (1) – Jun 2, 2018
Free
1 page
Loading next page...
1 Page
 
/lp/springer_journal/minoxidil-q9Dl20XyBC
Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-018-46894-z
Publisher site
See Article on Publisher Site

Abstract

Reactions 1704, p251 - 2 Jun 2018 Sinus node dysfunction accompanied by syncope: case report A 9-year-old girl developed sinus node dysfunction accompanied by syncope during treatment with minoxidil for alopecia [dosage and duration of treatment to reaction onset not stated]. The girl had been applying topical minoxidil for alopecia for two years. She presented for cardiac assessment before starting systemic minoxidil. She reported syncope once upon giving blood. She underwent cardiac monitoring for 24 hours using Holter monitor and asystolic attacks and sinus arrest were noted lasting for 4–6 seconds, accompanied by one episode of syncope in the morning hours. The girl’s treatment with minoxidil was discontinued. She was hospitalized for monitoring and scheduled for permanent pacemaker implantation. Transesophageal electrophysiological study was performed. After discontinuing minoxidil, the sinus arrest and sinus node dysfunction resolved, with normal sinus node function. Later, she was closely monitored for cardiac function. Implantation of the permanent pacemaker was not performed due to morbidity in paediatrics, and she was discharged home asymptomatically. Author comment: "The sinus node dysfunction experienced in this case was categorized as likely related to minoxidil (score 5), as assessed by the Naranjo adverse drug reaction probability assessment tool." Koca S, et al. Topical minoxidil treatment and sinus node dysfunciton in a child patient. Eastern Journal of Medicine 23: 121-123, No. 2, Apr-Jun 2018. Available from: URL: http://doi.org/10.5505/ejm.2018.47955 - Turkey 803322941 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704

Journal

Reactions WeeklySpringer Journals

Published: Jun 2, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off