Virchows Archiv (2018) 472:883–884 https://doi.org/10.1007/s00428-018-2385-2 EDITORIAL Sigurd F. Lax Published online: 4 June 2018 Springer-Verlag GmbH Germany, part of Springer Nature 2018 Virchows Archiv will regularly publish issues with a coordi- with poor prognosis, such as the mixed endometrial nated set of reviews in areas with important recent develop- carcinomas with a "low-grade" serous-like component, ments, but in volume insufficient to make it into a full review which will both profit from a “tailored” approach to issue. This issue contains such a miniseries of three review treatment. The TCGA data segregated endometrial articles in the area of gynecological pathology, two of which carcinoma into four prognostic categories, but this is not in are dealing with novel developments in molecular pathology conflict with the traditional type 1 and type 2 endometrial and histopathology of the uterus while the third addresses the carcinoma  as it only identifies one further subtype, the diagnostically challenging subject of benign proliferations of small group of POLE mutated carcinomas which have an the endometrium. excellent prognosis. The microsatellite instable and the low Goebel et al. (https://doi.org/10.1007/s00428-017-2279-8) copy number alteration groups cluster together, since they describe the evolution of the classification of endometrial show similar prognosis
Virchows Archiv – Springer Journals
Published: Jun 4, 2018
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