Minimizing the blood velocity differences between phase-contrast magnetic resonance imaging and computational fluid dynamics simulation in cerebral arteries and aneurysms

Minimizing the blood velocity differences between phase-contrast magnetic resonance imaging and... The integration of phase-contrast magnetic resonance images (PC-MRI) and computational fluid dynamics (CFD) is a way to obtain detailed information of patient-specific hemodynamics. This study proposes a novel strategy for imposing a pressure condition on the outlet boundary (called the outlet pressure) in CFD to minimize velocity differences between the PC-MRI measurement and the CFD simulation, and to investigate the effects of outlet pressure on the numerical solution. The investigation involved ten patient-specific aneurysms reconstructed from a digital subtraction angiography image, specifically on aneurysms located at the bifurcation region. To evaluate the effects of imposing the outlet pressure, three different approaches were used, namely: a pressure-fixed (P-fixed) approach; a flow rate control (Q-control) approach; and a velocity-field-optimized (V-optimized) approach. Numerical investigations show that the highest reduction in velocity difference always occurs in the V-optimized approach, where the mean of velocity difference (normalized by inlet velocity) is 19.3%. Additionally, the highest velocity differences appear near to the wall and vessel bifurcation for 60% of the patients, resulting in differences in wall shear stress. These findings provide a new methodology for PC-MRI integrated CFD simulation and are useful for understanding the evaluation of velocity difference between the PC-MRI and CFD. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Medical & Biological Engineering & Computing Springer Journals

Minimizing the blood velocity differences between phase-contrast magnetic resonance imaging and computational fluid dynamics simulation in cerebral arteries and aneurysms

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by International Federation for Medical and Biological Engineering
Subject
Biomedicine; Human Physiology; Biomedical Engineering; Imaging / Radiology; Computer Applications
ISSN
0140-0118
eISSN
1741-0444
D.O.I.
10.1007/s11517-017-1617-y
Publisher site
See Article on Publisher Site

Abstract

The integration of phase-contrast magnetic resonance images (PC-MRI) and computational fluid dynamics (CFD) is a way to obtain detailed information of patient-specific hemodynamics. This study proposes a novel strategy for imposing a pressure condition on the outlet boundary (called the outlet pressure) in CFD to minimize velocity differences between the PC-MRI measurement and the CFD simulation, and to investigate the effects of outlet pressure on the numerical solution. The investigation involved ten patient-specific aneurysms reconstructed from a digital subtraction angiography image, specifically on aneurysms located at the bifurcation region. To evaluate the effects of imposing the outlet pressure, three different approaches were used, namely: a pressure-fixed (P-fixed) approach; a flow rate control (Q-control) approach; and a velocity-field-optimized (V-optimized) approach. Numerical investigations show that the highest reduction in velocity difference always occurs in the V-optimized approach, where the mean of velocity difference (normalized by inlet velocity) is 19.3%. Additionally, the highest velocity differences appear near to the wall and vessel bifurcation for 60% of the patients, resulting in differences in wall shear stress. These findings provide a new methodology for PC-MRI integrated CFD simulation and are useful for understanding the evaluation of velocity difference between the PC-MRI and CFD.

Journal

Medical & Biological Engineering & ComputingSpringer Journals

Published: Feb 4, 2017

References

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