Middle East respiratory syndrome coronavirus (MERS-CoV): evidence and speculations

Middle East respiratory syndrome coronavirus (MERS-CoV): evidence and speculations In 2012, a novel human coronavirus emerged and was tentatively named “Middle East respiratory syndrome coronavirus” (MERS-CoV). The high mortality rate of MERS-CoV focused attention on the ecology of the virus. It has been found that MERS-CoV belongs to the group C lineage of the genus Betacoronavirus . Coronavirus surveillance studies in different populations of bats have suggested that they are probable reservoirs for this novel virus, and phylogenetic analysis of both the spike (S1) and RNA-dependent RNA polymerase proteins of MERS-CoV have revealed that it is related to bat viruses. Recently, the MERS-CoV and its neutralizing antibodies were detected in dromedary camels. Despite the limited number of reported cases of person-to-person transmission, the rapid evolution of the virus poses a continuous threat to humans worldwide. This paper reviews the current state of knowledge regarding the virology, clinical spectrum, evolution, diagnosis and treatment of MERS-CoV infections. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

Middle East respiratory syndrome coronavirus (MERS-CoV): evidence and speculations

Loading next page...
 
/lp/springer_journal/middle-east-respiratory-syndrome-coronavirus-mers-cov-evidence-and-be56DsxtKa
Publisher
Springer Vienna
Copyright
Copyright © 2014 by Springer-Verlag Wien
Subject
Biomedicine; Virology; Medical Microbiology; Infectious Diseases
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s00705-014-1995-5
Publisher site
See Article on Publisher Site

References

  • Receptor for new coronavirus found
    Butler, D
  • SARS: epidemiology
    Chan-Yeung, M; Xu, RH
  • Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
    Raj, VS; Mou, H; Smits, SL; Dekkers, DH; Müller, MA; Dijkman, R; Muth, D; Demmers, JA; Zaki, A; Fouchier, RA; Thiel, V; Drosten, C; Rottier, PJ; Osterhaus, AD; Bosch, BJ; Haagmans, BL
  • Human (non-severe acute respiratory syndrome) coronavirus infections in hospitalised children in France
    Vabret, A; Dina, J; Gouarin, S; Tripey, V; Brouard, J; Freymuth, F

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial