Mammalian Genome 8,357-361 (1997). e//o///e 9 Spnnger-Verlag New York Inc 1997 Microsatellite typing of CXB recombinant inbred and parental mouse strains Vily Panoutsakopoulou, Peter Spring, Laura Cort, James E. Sylvester, Kenneth J. Blank, Elizabeth P. Blankenhorn Department of Pathology, Medical College of Pennsylvania, Hahnemann School of Medicine, Allegheny University of the Health Sciences, Philadelphia, Pennsylvania 19102-1192, USA Received: 3 April 1996 / Accepted: 24 January 1997 The 13 CXB strains were typed for 153 SSLP markers. The Recombinant inbred (RI) strains derive from crosses between two SDPs are shown in Table 1. The distribution of tested markers on inbred mouse strains whose progeny are maintained under inde- Chromosomes (Chrs) 1-19 and X ranged from 0 to 23 cM, with an pendent inbreeding from the F 2 generation onward (Bailey 1971). RI strains are one of the most useful tools in mammalian genetics average of one SSLP marker every -8.6 cM. Since the mouse for relatively rapid and efficient mapping of genetic loci that differ genome is approximately 1600 cM, these markers scan almost between the two progenitor strains (Taylor 1989). The distribution 82% of the mouse genome. Several distal regions of a few chro- of parental phenotypes or genotypes
Mammalian Genome – Springer Journals
Published: Mar 21, 2009
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