Microinsemination, nuclear transfer, and cytoplasmic transfer: the application of new reproductive engineering techniques to mouse genetics

Microinsemination, nuclear transfer, and cytoplasmic transfer: the application of new... Review Incorporating Mouse Genome Mammalian Genome 12, 803–812 (2001). © Springer-Verlag New York Inc. 2001 DOI: 10.1007/s00335-001-4007-5 Microinsemination, nuclear transfer, and cytoplasmic transfer: the application of new reproductive engineering techniques to mouse genetics Atsuo Ogura, Narumi Ogonuki, Kaoru Takano, Kimiko Inoue Department of Veterinary Science, National Institute of Infectious Diseases, 1-23-1, Toyama, Shinjuku, Tokyo 162-8640, Japan Received: 30 June 2001 / Accepted: 16 July 2001 Mice are the most commonly used laboratory animals, owing to Microinsemination the availability of large amounts of information on their genetics and biology. As a result, numerous advanced techniques have been The development of intracytoplasmic sperm injection (ICSI) in the developed by using mouse embryos. Studies on murine develop- mouse. The first attempt to fertilize mammalian oocytes by mi- mental and reproductive biology are greatly facilitated by short croinsemination was made by Uehara and Yanagimachi in 1976. gestation and generation periods of 20 days and approximately 3 They demonstrated that an injected sperm head of the golden ham- months, respectively. Transgenic and knockout mice are of fun- ster developed into the male pronucleus after incorporation into the damental relevance to mammalian transgenic research. However, homologous ooplasm. Microinsemination of mice was first estab- in certain http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Microinsemination, nuclear transfer, and cytoplasmic transfer: the application of new reproductive engineering techniques to mouse genetics

Loading next page...
 
/lp/springer_journal/microinsemination-nuclear-transfer-and-cytoplasmic-transfer-the-lwqr8FFjgf
Publisher
Springer-Verlag
Copyright
Copyright © 2001 by Springer-Verlag New York Inc.
Subject
Life Sciences; Cell Biology; Anatomy; Zoology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s00335-001-4007-5
Publisher site
See Article on Publisher Site

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial