Access the full text.
Sign up today, get DeepDyve free for 14 days.
(2016)
2016) A novel viscoelastic-based ferrofluid for continu
K. McCloskey, L. Moore, M. Hoyos, Alex Rodriguez, J. Chalmers, M. Zborowski (2003)
Magnetophoretic Cell Sorting Is a Function of Antibody Binding CapacityBiotechnology Progress, 19
S. Khashan, E. Furlani (2012)
Effects of particle–fluid coupling on particle transport and capture in a magnetophoretic microsystemMicrofluidics and Nanofluidics, 12
K. McCloskey, J. Chalmers, M. Zborowski (2003)
Magnetic cell separation: characterization of magnetophoretic mobility.Analytical chemistry, 75 24
M. Vojtíšek, M. Tarn, N. Hirota, N. Pamme (2012)
Microfluidic devices in superconducting magnets: on-chip free-flow diamagnetophoresis of polymer particles and bubblesMicrofluidics and Nanofluidics, 13
G. Fonnum, C. Johansson, Astrid Molteberg, S. Mørup, E. Aksnes (2005)
Characterisation of Dynabeads® by magnetization measurements and Mössbauer spectroscopyJournal of Magnetism and Magnetic Materials, 293
J. Adams, U. Kim, H. Soh (2008)
Multitarget magnetic activated cell sorterProceedings of the National Academy of Sciences, 105
Almut Eisentrager, D. Vella, I. Griffiths (2014)
Particle capture efficiency in a multi-wire model for high gradient magnetic separationApplied Physics Letters, 105
S. Khashan, A. Alazzam, B. Mathew, M. Hamdan (2017)
Mixture Model for Biomagnetic Separation in Microfluidic SystemsJournal of Magnetism and Magnetic Materials, 442
J Zhang (2016)
A novel viscoelastic-based ferrofluid for continuous sheathless microfluidic separation of nonmagnetic microparticlesLab Chip, 16
Jun Zhang, Weihua Li, M. Li, G. Alici, N. Nguyen (2014)
Particle inertial focusing and its mechanism in a serpentine microchannelMicrofluidics and Nanofluidics, 17
(2005)
Drive A (2005) A microfluidic system for contin
T. Kong, H. E., H. Sugiarto, H. Liew, Xinghua Wang, W. Lew, N. Nguyen, Yong Chen (2011)
An efficient microfluidic sorter: implementation of double meandering micro striplines for magnetic particles switchingMicrofluidics and Nanofluidics, 10
S. Khashan, A. Alazzam, E. Furlani (2014)
Computational Analysis of Enhanced Magnetic Bioseparation in Microfluidic Systems with Flow-Invasive Magnetic ElementsScientific Reports, 4
U. Kim, H. Soh (2009)
Simultaneous sorting of multiple bacterial targets using integrated dielectrophoretic-magnetic activated cell sorter.Lab on a chip, 9 16
Q. Ramadan, D. Poenar, Chen Yu (2009)
Customized trapping of magnetic particlesMicrofluidics and Nanofluidics, 6
D. Fletcher (1991)
Fine particle high gradient magnetic entrapmentIEEE Transactions on Magnetics, 27
S. Khashan, E. Furlani (2013)
Coupled particle–fluid transport and magnetic separation in microfluidic systems with passive magnetic functionalityJournal of Physics D: Applied Physics, 46
Tung‐yu Ying, S. Yiacoumi, C. Tsouris (2000)
High-gradient magnetically seeded filtrationChemical Engineering Science, 55
S. Khashan, E. Furlani (2014)
Scalability analysis of magnetic bead separation in a microchannel with an array of soft magnetic elements in a uniform magnetic fieldSeparation and Purification Technology, 125
Ki-Ho Han, A. Frazier (2005)
A Microfluidic System for Continuous Magnetophoretic Separation of Suspended Cells Using Their Native Magnetic Properties, 1
D. Inglis, R. Riehn, R. Austin, J. Sturm (2004)
Continuous microfluidic immunomagnetic cell separationApplied Physics Letters, 85
A. Alazzam, B. Mathew, S. Khashan (2017)
Microfluidic Platforms for Bio-applications
Hesam Babahosseini, V. Srinivasaraghavan, Zongmin Zhao, Frank Gillam, Elizabeth Childress, Jeannine Strobl, Webster Santos, Chenming Zhang, Masoud Agah (2015)
The impact of sphingosine kinase inhibitor-loaded nanoparticles on bioelectrical and biomechanical properties of cancer cellsLab on a Chip, 16
S. Khashan, E. Elnajjar, Y. Haik (2011)
Numerical simulation of the continuous biomagnetic separation in a two-dimensional channelInternational Journal of Multiphase Flow, 37
Jonathan Adams, H. Soh (2009)
Perspectives on Utilizing Unique Features of Microfluidics Technology for Particle and Cell SortingJournal of Laboratory Automation, 14
S. Khashan, S. Dagher, A. Alazzam, B. Mathew, A. Hilal-Alnaqbi (2017)
Microdevice for continuous flow magnetic separation for bioengineering applicationsJournal of Micromechanics and Microengineering, 27
N. Pamme, A. Manz (2004)
On-chip free-flow magnetophoresis: continuous flow separation of magnetic particles and agglomerates.Analytical chemistry, 76 24
Ki-Ho Han, A. Frazier (2004)
Continuous magnetophoretic separation of blood cells in microdevice formatJournal of Applied Physics, 96
Xinhui Lou, Jiangrong Qian, Yi Xiao, L. Viel, A. Gerdon, E. Lagally, P. Atzberger, T. Tarasow, A. Heeger, H. Soh (2009)
Micromagnetic selection of aptamers in microfluidic channelsProceedings of the National Academy of Sciences, 106
M. Hoyos, L. Moore, K. McCloskey, K. McCloskey, S. Margel, Merav Zuberi, J. Chalmers, M. Zborowski (2000)
Study of magnetic particles pulse-injected into an annular SPLITT-like channel inside a quadrupole magnetic field.Journal of chromatography. A, 903 1-2
Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
In magnetophoresis-based microfluidic systems, the free-flow sorting is achieved by incrementally navigating the magnetic target toward a designated outlet. This is typically enabled using high-gradient magnetic concentrators (HGMCs), axially aligned or slightly slanted with the streaming sample flow. Such axial and incremental magnetic manipulation critically constraints the throughput and the number of targets that can be sorted simultaneously. To overcome these constraints, we present an alternative repulsion-based sorting method. The repulsion force is due that induced, over a limited angular expanse, around a single ferromagnetic wire. The wire is positioned transversally against the focused sample flow. Differentially repelled by the repulsive force, each target deflects from its focused path to follow a ribbon-like trajectory that leads to a spatially addressable outlet. The mediated sorting takes place more rapidly and is confined to the region facing the transversal wire. More importantly, the introduced concept design allows for a throughput that is geometrically scalable with the length of the wire. The functionality of the systems is demonstrated experimentally and numerically to yield the simultaneous and complete multi-target sorting of two and more magnetic beads.
Microfluids and Nanofluids – Springer Journals
Published: Jun 6, 2018
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.