Mexiletine

Mexiletine Reactions 1680, p231 - 2 Dec 2017 Extremities tremor and dizziness: 3 case reports In a retrospective cohort analysis, 3 patients [ages and sexes not stated] were described, who developed dizziness or extremities tremor during treatment with mexiletine [dosages, routes, duration of treatment to reactions onsets and outcomes not stated]. The patients, with recurrent ventricular tachyarrhythmia, were started on daily doses of mexiletine. One patient developed extremities tremor and one patient developed dizziness. The patients were continued on the mexiletine therapy. One patient developed severe dizziness, after which the mexiletine therapy was stopped. Author comment: "In four (23.5%) patients, mild temporary side effects were observed, which did not require discontinuation of therapy. . . (in one patient extremities tremor, in one patient dizziness)." "Only in three (17.6%) patients severe side effects of mexiletine treatment occurred. . . (in one patient severe dizziness)." Sobiech M, et al. Efficacy and tolerability of mexiletine treatment in patients with recurrent ventricular tachyarrhythmias and implantable cardioverter-defibrillator shocks. Kardiologia Polska 75: 1027-1032, No. 10, 2017. Available from: URL: http://doi.org/10.5603/KP.2017.0189 - Poland 803284536 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Mexiletine

Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Publisher
Springer International Publishing
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-017-39162-3
Publisher site
See Article on Publisher Site

Abstract

Reactions 1680, p231 - 2 Dec 2017 Extremities tremor and dizziness: 3 case reports In a retrospective cohort analysis, 3 patients [ages and sexes not stated] were described, who developed dizziness or extremities tremor during treatment with mexiletine [dosages, routes, duration of treatment to reactions onsets and outcomes not stated]. The patients, with recurrent ventricular tachyarrhythmia, were started on daily doses of mexiletine. One patient developed extremities tremor and one patient developed dizziness. The patients were continued on the mexiletine therapy. One patient developed severe dizziness, after which the mexiletine therapy was stopped. Author comment: "In four (23.5%) patients, mild temporary side effects were observed, which did not require discontinuation of therapy. . . (in one patient extremities tremor, in one patient dizziness)." "Only in three (17.6%) patients severe side effects of mexiletine treatment occurred. . . (in one patient severe dizziness)." Sobiech M, et al. Efficacy and tolerability of mexiletine treatment in patients with recurrent ventricular tachyarrhythmias and implantable cardioverter-defibrillator shocks. Kardiologia Polska 75: 1027-1032, No. 10, 2017. Available from: URL: http://doi.org/10.5603/KP.2017.0189 - Poland 803284536 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680

Journal

Reactions WeeklySpringer Journals

Published: Dec 2, 2017

References

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