Reactions 1680, p229 - 2 Dec 2017
Limited pneumothorax, blue urine and cough with
expectoration of blue sputum: 8 case reports
In a study, eight patients [ages and sexes not stated] were
described, who developed limited pneumothorax (4 patients),
blue urine (3 patients) and cough with expectoration of blue
sputum (3 patients) during injection of methylthioninium
chloride [methylene blue; dosage not stated].
All eight patients had nodules in the lungs. All patients
underwent CT-guided labelling of the nodules with injection of
methylthioninium chloride for video-assisted thoracic surgery
(VATS). Subsequently, all eight patients developed
complications, which included limited pneumothorax in four
patients, blue urine in three patients and coughing with blue
sputum expectoration for a few minutes in three patients
[times to reactions onsets not stated; not all outcomes stated].
Author comment: "Herein we discuss our experience with
CT-guided [methylthioninium chloride] labelling" "We did not
observe any major complication. Three of the patients had
small pneumothorax that did not require chest tube drainage.
Three of the patients suffered from coughing with blue
sputum expectoration for a few minutes after the [labelling],
without any clinical significance. Also, two patients’ urine
[colour] changed to blue for one day"
Findik G, et al. Computed Tomography-Guided Methylene Blue Labeling Prior to
Thoracoscopic Resection of Small Deeply Placed Pulmonary NodulesDo We
Really Need Palpation?. Thoracic and Cardiovascular Surgeon 65: 387-391, No. 5,
Aug 2017. Available from: URL: http://doi.org/10.1055/s-0036-1598019 -
Reactions 2 Dec 2017 No. 16800114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved