Reactions 1704, p245 - 2 Jun 2018 Oidiodendron cerealis infection: case report A 68-year-old woman developed Oidiodendron cerealis infection while receiving immunosuppresive treatment with methotrexate and prednisone for rheumatoid arthritis [not all routes stated; dosage and time to reaction onset not stated]. The woman, who had rheumatoid arthritis, had been receiving treatment with methotrexate and oral prednisone. She presented with pain in the left hand. Flare of rheumatoid arthritis was presumed, and her oral prednisolone dose was increased by her general practitioner. After several weeks, she presented to the hospital with increased pain in the left hand and fluctuant erythematous nodules in her left arm with sporotrichoid distribution. Analysis of her history revealed recent activity of re-potting the plants. Cellulitis was suspected and bacterial and fungal swabs were collected for biopsies. The woman’s treatment was started with unspecified IV antibiotics and amphotericin. Additionally, one dose of itraconazole was also administered. Despite receiving the treatment, she developed sepsis and later died. Oidiodendron cerealis fungi was identified in culture tests from the tissue material collected from a nodule, which was also isolated on PCR. Later, the spores were also identified on a Gomori- methenamine stain. Author comment: "Immunosuppression of the patient is likely to be contributory, as invasive fungal infections, whilst difficult to diagnose, are becoming increasingly common in immunocompromised patients. Any fungus could be considered a potential cause in the immunosuppressed patient, including this rare Oidiodendron cerealis." Sideris E, et al. Case report of oidiodendron cerealis infection in the immunosuppressed patient. Australasian Journal of Dermatology 59 (Suppl. 1): 105, May 2018. Available from: URL: http://doi.org/10.1111/ajd.17_12815 [abstract] - Australia 803323843 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704
Reactions Weekly – Springer Journals
Published: Jun 2, 2018
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