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OBES SURG (2017) 27:3258–3266 DOI 10.1007/s11695-017-2779-2 ORIGINAL CONTRIBUTIONS Metabolic Effects of Sleeve Gastrectomy and Laparoscopic Greater Curvature Plication: an 18-Month Prospective, Observational, Open-Label Study 1 2 3 1 Marek Bužga & Zdeněk Švagera & Hana Tomášková & Karel Hauptman & Pavol Holéczy Published online: 3 July 2017 Springer Science+Business Media, LLC 2017 Abstract low-density lipoprotein cholesterol, testosterone, estradiol, Background Laparoscopic greater curvature plication (LGCP) leptin, adiponectin, ghrelin, fatmass, and lean body mass. is an innovative restrictive technique designed to reduce gastric Results Significant weight-loss and a reduced body composi- volume by plication at the region of greater curvature. The tion resulted from either procedure vs. baseline (i.e., pre-sur- long-term efficacy, safety, and the metabolic effects of this pro- gery), with levels of fasting glucose and glycated hemoglobin cedure are the subject of this study. also showing statistically significant reductions (at 3 and Methods One hundred twenty-seven patients were enrolled; 18 months for either surgery). Intergroup comparisons for 84 underwent laparoscopic sleeve gastrectomy (LSG) and 43, glycemic parameters yielded no statistically significant differ- LGCP. LSG and LGCP were then compared during long-term ences. However, a dramatic reduction in ghrelin was detected follow-ups in terms of glycemic control, hormone and lipid
Obesity Surgery – Springer Journals
Published: Jul 3, 2017
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