Metabolic Effects of Sleeve Gastrectomy and Laparoscopic Greater Curvature Plication: an 18-Month Prospective, Observational, Open-Label Study

Metabolic Effects of Sleeve Gastrectomy and Laparoscopic Greater Curvature Plication: an 18-Month... OBES SURG (2017) 27:3258–3266 DOI 10.1007/s11695-017-2779-2 ORIGINAL CONTRIBUTIONS Metabolic Effects of Sleeve Gastrectomy and Laparoscopic Greater Curvature Plication: an 18-Month Prospective, Observational, Open-Label Study 1 2 3 1 Marek Bužga & Zdeněk Švagera & Hana Tomášková & Karel Hauptman & Pavol Holéczy Published online: 3 July 2017 Springer Science+Business Media, LLC 2017 Abstract low-density lipoprotein cholesterol, testosterone, estradiol, Background Laparoscopic greater curvature plication (LGCP) leptin, adiponectin, ghrelin, fatmass, and lean body mass. is an innovative restrictive technique designed to reduce gastric Results Significant weight-loss and a reduced body composi- volume by plication at the region of greater curvature. The tion resulted from either procedure vs. baseline (i.e., pre-sur- long-term efficacy, safety, and the metabolic effects of this pro- gery), with levels of fasting glucose and glycated hemoglobin cedure are the subject of this study. also showing statistically significant reductions (at 3 and Methods One hundred twenty-seven patients were enrolled; 18 months for either surgery). Intergroup comparisons for 84 underwent laparoscopic sleeve gastrectomy (LSG) and 43, glycemic parameters yielded no statistically significant differ- LGCP. LSG and LGCP were then compared during long-term ences. However, a dramatic reduction in ghrelin was detected follow-ups in terms of glycemic control, hormone and lipid http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Obesity Surgery Springer Journals

Metabolic Effects of Sleeve Gastrectomy and Laparoscopic Greater Curvature Plication: an 18-Month Prospective, Observational, Open-Label Study

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Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media, LLC
Subject
Medicine & Public Health; Surgery
ISSN
0960-8923
eISSN
1708-0428
D.O.I.
10.1007/s11695-017-2779-2
Publisher site
See Article on Publisher Site

Abstract

OBES SURG (2017) 27:3258–3266 DOI 10.1007/s11695-017-2779-2 ORIGINAL CONTRIBUTIONS Metabolic Effects of Sleeve Gastrectomy and Laparoscopic Greater Curvature Plication: an 18-Month Prospective, Observational, Open-Label Study 1 2 3 1 Marek Bužga & Zdeněk Švagera & Hana Tomášková & Karel Hauptman & Pavol Holéczy Published online: 3 July 2017 Springer Science+Business Media, LLC 2017 Abstract low-density lipoprotein cholesterol, testosterone, estradiol, Background Laparoscopic greater curvature plication (LGCP) leptin, adiponectin, ghrelin, fatmass, and lean body mass. is an innovative restrictive technique designed to reduce gastric Results Significant weight-loss and a reduced body composi- volume by plication at the region of greater curvature. The tion resulted from either procedure vs. baseline (i.e., pre-sur- long-term efficacy, safety, and the metabolic effects of this pro- gery), with levels of fasting glucose and glycated hemoglobin cedure are the subject of this study. also showing statistically significant reductions (at 3 and Methods One hundred twenty-seven patients were enrolled; 18 months for either surgery). Intergroup comparisons for 84 underwent laparoscopic sleeve gastrectomy (LSG) and 43, glycemic parameters yielded no statistically significant differ- LGCP. LSG and LGCP were then compared during long-term ences. However, a dramatic reduction in ghrelin was detected follow-ups in terms of glycemic control, hormone and lipid

Journal

Obesity SurgerySpringer Journals

Published: Jul 3, 2017

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