Breast Cancer Res Treat (2017) 165:273–283 DOI 10.1007/s10549-017-4324-3 REVIEW Meta-analysis of pre-operative magnetic resonance imaging (MRI) and surgical treatment for breast cancer 1 2 3 • • Nehmat Houssami Robin M. Turner Monica Morrow Received: 24 April 2017 / Accepted: 29 May 2017 / Published online: 6 June 2017 Springer Science+Business Media New York 2017 Abstract ﬁndings were shown in analyses stratiﬁed by study-level Background Although there is no consensus on whether median age. Secondary analyses did not ﬁnd statistical pre-operative MRI in women with breast cancer (BC) evidence of an effect of MRI on the rates of re-excision, re- beneﬁts surgical treatment, MRI continues to be used pre- operation, or positive margins; however, MRI was signif- operatively in practice. This meta-analysis examines the icantly associated with increased odds of receiving con- association between pre-operative MRI and surgical out- tralateral prophylactic mastectomy [OR 1.91 (1.25, 2.91); comes in BC. p = 0.003]. Subgroup analysis for ILC did not ﬁnd any Methods A systematic review was performed to identify association between MRI and the odds of receiving mas- studies reporting quantitative data on pre-operative MRI tectomy [OR 1.00 (0.75, 1.33); p = 0.988] or the odds of and surgical outcomes
Breast Cancer Research and Treatment – Springer Journals
Published: Jun 6, 2017
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