Melatonin effect on the regeneration of the flatworm Girardia tigrina

Melatonin effect on the regeneration of the flatworm Girardia tigrina The melatonin effect on the anterior and posterior ends of a free-living flatworm Girardia tigrina was studied, as well as the variability of the mitotic activity of the stem cells (neoblasts) in the anterior and posterior postblasteme. This hormone may inhibit the regeneration of the anterior end of the animal in the physiologic-friendly concentrations of 10−10–10−5 M by suppressing the mitotic activity of the neoblasts. This hormone does not affect the posterior end’s regeneration; thus, its regeneration effect is significantly elective. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Developmental Biology Springer Journals

Melatonin effect on the regeneration of the flatworm Girardia tigrina

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Publisher
Springer Journals
Copyright
Copyright © 2009 by Pleiades Publishing, Ltd.
Subject
Life Sciences; Animal Anatomy / Morphology / Histology; Developmental Biology
ISSN
1062-3604
eISSN
1608-3326
D.O.I.
10.1134/S1062360409060083
Publisher site
See Article on Publisher Site

Abstract

The melatonin effect on the anterior and posterior ends of a free-living flatworm Girardia tigrina was studied, as well as the variability of the mitotic activity of the stem cells (neoblasts) in the anterior and posterior postblasteme. This hormone may inhibit the regeneration of the anterior end of the animal in the physiologic-friendly concentrations of 10−10–10−5 M by suppressing the mitotic activity of the neoblasts. This hormone does not affect the posterior end’s regeneration; thus, its regeneration effect is significantly elective.

Journal

Russian Journal of Developmental BiologySpringer Journals

Published: Dec 3, 2009

References

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