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Medication-related harm common and costly in elderly

Medication-related harm common and costly in elderly Reactions 1704, p10 - 2 Jun 2018 Medication-related harm common and costly in elderly Medication-related harm (MRH) appears to be common and costly after discharge from hospital in older patients receiving polypharmacy, according to findings of a prospective UK study published in the British Journal of Clinical Pharmacology. This observational study investigated the incidence, severity, preventability and costs of MRH in 1280 older patients (≥65 years; median 82 years) after discharge from five hospitals in Southern England. Senior pharmacists followed up patients for eight weeks, and used data from hospital readmission reviews, telephone interviews with patients, and primary care records, to assess MRH and MRH-related National Health Service (NHS) utilisation. MRH was identified in 37% of patients (556 events per 1000 discharges), and most cases (81%) were serious. Overall, 52% of cases of MRH were considered to be potentially preventable; 10.7% were definitely preventable and 41.2% were possibly preventable. MRH resulted in death in four cases. The most frequent MRH events were gastrointestinal (25%) or neurological (18%). The drugs with the highest incidence of MRH events per 1000 prescriptions were opioid analgesics (399), antibacterials (189) and benzodiazepines (185). The majority of patients (79%) required healthcare during follow-up; the incidence http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Medication-related harm common and costly in elderly

Reactions Weekly , Volume 1704 (1) – Jun 2, 2018

Medication-related harm common and costly in elderly

Abstract

Reactions 1704, p10 - 2 Jun 2018 Medication-related harm common and costly in elderly Medication-related harm (MRH) appears to be common and costly after discharge from hospital in older patients receiving polypharmacy, according to findings of a prospective UK study published in the British Journal of Clinical Pharmacology. This observational study investigated the incidence, severity, preventability and costs of MRH in 1280 older patients (≥65 years; median 82 years) after discharge from...
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References (1)

Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
DOI
10.1007/s40278-018-46653-7
Publisher site
See Article on Publisher Site

Abstract

Reactions 1704, p10 - 2 Jun 2018 Medication-related harm common and costly in elderly Medication-related harm (MRH) appears to be common and costly after discharge from hospital in older patients receiving polypharmacy, according to findings of a prospective UK study published in the British Journal of Clinical Pharmacology. This observational study investigated the incidence, severity, preventability and costs of MRH in 1280 older patients (≥65 years; median 82 years) after discharge from five hospitals in Southern England. Senior pharmacists followed up patients for eight weeks, and used data from hospital readmission reviews, telephone interviews with patients, and primary care records, to assess MRH and MRH-related National Health Service (NHS) utilisation. MRH was identified in 37% of patients (556 events per 1000 discharges), and most cases (81%) were serious. Overall, 52% of cases of MRH were considered to be potentially preventable; 10.7% were definitely preventable and 41.2% were possibly preventable. MRH resulted in death in four cases. The most frequent MRH events were gastrointestinal (25%) or neurological (18%). The drugs with the highest incidence of MRH events per 1000 prescriptions were opioid analgesics (399), antibacterials (189) and benzodiazepines (185). The majority of patients (79%) required healthcare during follow-up; the incidence

Journal

Reactions WeeklySpringer Journals

Published: Jun 2, 2018

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