PharmacoEconomics & Outcomes News 804, p19 - 2 Jun 2018 Mechanical circulatory support costly in paediatric heart transplant Mechanical circulatory support (MCS) as a bridge to heart transplantation (HT) in children is associated with greater costs during the entire HT hospitalisation, compared with children without MCS. This is the main finding of a US study that assessed length of stay (LOS) and costs in children bridged to HT with either a ventricular assist device (VAD) or extracorporeal membrane oxygenation (ECMO), compared with no MCS. The study used linked 2002–2016 data from the Scientific Registry of Transplant Recipients (SRTR) and the Pediatric Health Information System (PHIS). The analysis of data for 2873 paediatric HT recipients showed that total median LOS was significantly longer for patients supported with VAD or ECMO at the time of HT, compared with no MCS (78 and 68 days, respectively, vs 44 days). In addition, both VAD and ECMO were associated with significantly higher total hospitalisation costs, compared with no MCS ($US755 345 and $808 771, respectively, vs $457 086; 2016 values). Although total hospitalisation costs were not significantly different between patients on VAD or ECMO, the distribution of costs across the pre- and post-HT periods was significantly different. VAD- supported patients had higher costs than ECMO- supported patients during the pre-HT period but lower costs during the post-HT period. "Discharging patients on VAD support awaiting HT represents a strategy to reduce costs in this population," suggest the researchers. Godown J, et al. Mechanical circulatory support costs in children bridged to heart transplantation - analysis of a linked database. American Heart Journal 201: 77-85, 6 Apr 2018. Available from: URL: http://doi.org/10.1016/ j.ahj.2018.04.006 803324250 1173-5503/18/0804-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved PharmacoEconomics & Outcomes News 2 Jun 2018 No. 804
PharmacoEconomics & Outcomes News – Springer Journals
Published: Jun 2, 2018
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