Arch Gynecol Obstet (2017) 296:475–482 DOI 10.1007/s00404-017-4457-y MATERNAL-FETAL MEDICINE Maternal serum homocysteine and uterine artery Doppler as predictors of preeclampsia and poor placentation 1 1 1 1 1 Ahmed M. Maged · Hany Saad · Hadeer Meshaal · Emad Salah · Suzy Abdelaziz · 1 2 3 Eman Omran · Wesam S. Deeb · Maha Katta Received: 27 February 2017 / Accepted: 5 July 2017 / Published online: 8 July 2017 © Springer-Verlag GmbH Germany 2017 Abstract Results 453 pregnant women completed the follow-up Purpose The aim of this study was to evaluate the role of the study. The tHcy and Ut-A resistance index were of maternal serum total Homocysteine (tHcy) and uterine significantly higher in women who developed PE, IUGR, artery (Ut-A) Doppler as predictors of preeclampsia and other complications when compared to controls (PE), intrauterine growth restriction (IUGR), and other (tHcy: 7.033 ± 2.744, 6.321 ± 3.645, and 6.602 ± 2.469 complications related to poor placentation. vs 4.701 ± 2.082 μmol/L, respectively, p value <0.001 Patients and methods A prospective cohort study was and Ut-A resistance index: 0.587 ± 0.072, 0.587 ± 0.053, conducted on 500 women with spontaneous pregnancies. and 0.597 ± 0.069 vs 0.524 ± 0.025, respectively, p value tHcy was measured at 15–19 weeks, and then, Ut-A <0.001). The use of
Archives of Gynecology and Obstetrics – Springer Journals
Published: Jul 8, 2017
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