Mammalian Genome 8, 778–780 (1997). © Springer-Verlag New York Inc. 1997 Mapping the valosin-containing protein (VCP) gene on human Chromosome 9 and mouse Chromosome 4, and a likely pseudogene on the mouse X Chromosome 1 2 1 Jacqueline Hoyle, Kim H. Tan, Elizabeth M.C. Fisher Neurogenetics Unit, Imperial College of Medicine at St. Mary’s, Norfolk Place, London W2 1PG, UK Department of Life Sciences, Winston-Salem State University, 601 Martin Luther King Jr. Drive, Winston-Salem, North Carolina 27110, USA Received: 3 May 1997 / Accepted: 8 June 1997 The mammalian valosin-containing protein (VCP) is thought to be chromosomal cell hybrid panel, (ii) three partial human Chromo- an important factor in mediating protein-protein interactions in some (Chr) 9 cell hybrids: Dora 34.4, CJ9q, and SV340, and (iii) clathrin-mediated membrane transfer pathways (Acharya et al. the Genebridge 4 mapping panel. The results of these amplifica- 1995; Rabouille et al. 1995; Zhang et al. 1994). Since only a small tions were consistent with our FISH mapping, and the Genebridge fraction of VCP is complexed to clathrin in the cell, it has been 4 data place VCP 3.87 cR distal of the marker AFM326VD1. suggested that VCP may also have other as yet unknown
Mammalian Genome – Springer Journals
Published: Oct 1, 1997
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