Short Communications Incorporating Mouse Genome Mammalian Genome 12, 250–252 (2001). © Springer-Verlag New York Inc. 2001 DOI: 10.1007/s003350010264 Mapping of the pogo gene, a new ataxic mutant from Korean wild mice, on central mouse Chromosome 8 1 1 1 1 2 3 Byung-Hwa Hyun, Myung-Soo Kim, Yang-Kyu Choi, Won-Kee Yoon, Jun-Gyo Suh, Young-Gil Jeong, 4 1 Soon-Kwon Park, Chul-Ho Lee Genetic Resources Center, Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong Taejon, 305-600, Korea Hallym University, Chunchon, Korea Konyang University, Nonsan, Korea Korea University, Seoul, Korea Received: 31 March 2000 / Accepted: 28 October 2000 Three male mice of Korean wild stock, named KJR/MsKist, ex- calbindin immunocytochemistry showed deposited peroxidase re- hibiting abnormal behavior were discovered in November 1995. action product throughout all Purkinje cells, including the somata, They were mated to normal sib females, and brother-sister mating dendrites, dendritic spines, and axons, in both normal wild-type was continued. Affected mice showing ataxia were recovered in and affected mutant mice. The cross-sectioned Purkinje cell den- the succeeding generations. These were characterized by a wobbly drites of affected mice were larger than those of normal mice gait and a tendency to fall over, which appeared at about
Mammalian Genome – Springer Journals
Published: Mar 1, 2001
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