Mapping of the otogelin gene (OTGN) to mouse Chromosome 7 and human Chromosome 11p14.3: a candidate for human autosomal recessive nonsyndromic deafness DFNB18

Mapping of the otogelin gene (OTGN) to mouse Chromosome 7 and human Chromosome 11p14.3: a... Short Communications Incorporating Mouse Genome Mammalian Genome 10, 520–522 (1999). © Springer-Verlag New York Inc. 1999 Mapping of the otogelin gene (OTGN) to mouse Chromosome 7 and human Chromosome 11p14.3: a candidate for human autosomal recessive nonsyndromic deafness DFNB18 1 2 1 Martine Cohen-Salmon, Marie-Genevie `ve Mattei, Christine Petit Unite´de Ge ´ne ´tique des De ´ficits Sensoriels, CNRS URA 1968, Institut Pasteur, 25 rue du Dr Roux, 75724, Paris Cedex 15, France Unite´de Ge ´ne ´tique Me ´dicale et De ´veloppement, INSERM U406, Faculte´de Me ´decine, 27 boulevard Jean Moulin, 13385 Marseille Cedex 05, France Received: 6 October 1998 / Accepted: 30 December 1998 Identifying the genes responsible for isolated deafness in man is an In order to investigate whether otogelin could be involved in important challenge. Nearly one in every 1000 children is affected hearing impairment in mouse and/or human, we mapped the cor- by hearing impairment at birth or before 2 years of age, that is, in responding genes on mouse and human chromosomes. Localiza- the prelingual period. Of these cases, approximately 65% are ge- tion on the mouse chromosomes was performed by fluorescence in netically determined, and the vast majority of these (80%) are situ hybridization http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Mapping of the otogelin gene (OTGN) to mouse Chromosome 7 and human Chromosome 11p14.3: a candidate for human autosomal recessive nonsyndromic deafness DFNB18

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Publisher
Springer-Verlag
Copyright
Copyright © 1999 by Springer-Verlag New York Inc.
Subject
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359901033
Publisher site
See Article on Publisher Site

Abstract

Short Communications Incorporating Mouse Genome Mammalian Genome 10, 520–522 (1999). © Springer-Verlag New York Inc. 1999 Mapping of the otogelin gene (OTGN) to mouse Chromosome 7 and human Chromosome 11p14.3: a candidate for human autosomal recessive nonsyndromic deafness DFNB18 1 2 1 Martine Cohen-Salmon, Marie-Genevie `ve Mattei, Christine Petit Unite´de Ge ´ne ´tique des De ´ficits Sensoriels, CNRS URA 1968, Institut Pasteur, 25 rue du Dr Roux, 75724, Paris Cedex 15, France Unite´de Ge ´ne ´tique Me ´dicale et De ´veloppement, INSERM U406, Faculte´de Me ´decine, 27 boulevard Jean Moulin, 13385 Marseille Cedex 05, France Received: 6 October 1998 / Accepted: 30 December 1998 Identifying the genes responsible for isolated deafness in man is an In order to investigate whether otogelin could be involved in important challenge. Nearly one in every 1000 children is affected hearing impairment in mouse and/or human, we mapped the cor- by hearing impairment at birth or before 2 years of age, that is, in responding genes on mouse and human chromosomes. Localiza- the prelingual period. Of these cases, approximately 65% are ge- tion on the mouse chromosomes was performed by fluorescence in netically determined, and the vast majority of these (80%) are situ hybridization

Journal

Mammalian GenomeSpringer Journals

Published: May 1, 1999

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