Short Communications Mammalian Genome 8, 37-38 (1997). 9 Springer-Veflag New York Inc. 1997 Mapping of a haploid transcribed and translated sperm-specific gene to the mouse X Chromosome S.B. Moss, 1'2 H. VanScoy, 1 G.L. Gerton 1'2 1Center for Research on Reproduction and Women's Health, Department of Obstetrics and Gynecology, 36th and Hamilton Walk, John Morgan Building, Room 305, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104-6080, USA 2Department of Cell and Developmental Biology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, 19104, USA Received: 6 August 1996 / Accepted: 10 September 1996 AKAP82 is the major fibrous sheath protein of the mouse sperm DXBirl AKAP82 tFscl) flagellum and a member of the A Kinase Anchor Protein (AKAP) family of polypeptides (Carrera et al. 1994). AKAPs anchor pro- Fig. 1. Schematic map of the mouse X Chr show- tein kinase A to specific subcellular locations via the regulatory ing the position of AKAP82. The gene maps to the subunit of the enzyme (Rubin 1994), indicating that AKAP82 acts very proximal end of the X Chr, co-segregating as a scaffolding protein for regulatory proteins in the flagellum. As with DXMit26, DXBirl, and three yeast-to-human part of our studies on this germ cell-specific
Mammalian Genome – Springer Journals
Published: Mar 23, 2009
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